SP7000P 5-HT1B / HTR1B antibody
see related secondary antibodiessee all 12 5-HT1B / HTR1B products
0.1 mg / US$ 405
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti 5-HT1B / HTR1B
Synonyms
5-Hydroxytryptamine Receptor 1B, Serotonin Receptor 1B, 5-HT-1D-beta, 5-HT-1B, S12, HTR1DB, , Serotonin 1D beta receptor, serotonin 5-ht-1b receptor, serotonin 5-ht-1d-beta receptor
Product review
Please read our product review about 5-HT1B / HTR1B : Antibodies to 5-hydroxytryptamine (Serotonin) Receptors.
Product Description
Rabbit anti 5-HT1B / HTR1B , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | SP7000P |
| Swiss Prot. No. | P28564 |
| Quantity | 0.1 mg |
| Price | US$ 405 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP7000P.pdf |
Datasheet Extract
| Concentration | 0.5 mg/ml |
| Background | Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems (1). Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase (2). Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum (3,4). The in situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei (5). |
| Immunogen | Mixture of synthetic peptides corresponding to amino acids 8-26 and 263-278 of rat 5-HT1BR (6). Swiss Num.: P28564 |
| Format | State: Liquid IgG fraction Purification: Protein G chromatography BufferSystem: PBS pH 7.2 with 0.02% sodium azide. |
| Applications | Western blotting (use at 1 µg/ml). |
| Specificity | This polyclonal antibody detects 5-HT1BR in brain cell lysates. Species: Human, mouse, and rat. |
| Storage | Store the antibody at 4-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Petrouka, SJ. Trends Neurosci. 11: 486-500 (1998).
2. De Vivo, M., Mayani, S. J. Pharmacol. Exp. Ther. 238: 248-252 (1986). 3. Pazos, A., Cortes, R., Palacios, JM. Brain Res. 345: 231-249 (1985). 4. Pazos, A. and Palcios, JM. Brain Res. 346: 205-230 (1985). 5. Bruinvels, AT.,et al. Neurophramacol. 33: 367-386 (1994). 6. Voigt,M.M.,et al. EMBO J. 10 (13) 4017-4023 (1991) |
| Pictures | Western blot analysis of 5-HT1BR in human brain lysate with anti-5-HT1BR pcAb (Cat. SP7000). A protein band of approximate molecular weight of 40-41kDa was detected.
|
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP7000P 5-HT1B / HTR1B '.
