SP5328P DNA Methyltransferase 3a (Dnmt3a) antibody
see related secondary antibodiessee all 15 DNA Methyltransferase 3a products
0.1 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti DNA Methyltransferase 3a (Dnmt3a) -
Synonyms
DNMT3A DNMT3A2 M.HsaIIIA
Product review
Please read our product review about DNA Methyltransferase 3a (Dnmt3a): Antibodies to DNA methyltransferases (Dnmt Family).
Product Description
Rabbit anti DNA Methyltransferase 3a (Dnmt3a) -, Presentation: Aff - Purified. Product is tested for Westernblot / Immunoblot ( WB )
Properties
| Applications | Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP5328P |
| Quantity | 0.1 mg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP5328P.pdf |
Datasheet Extract
| Polyclonal Antibody to //DNA Methyltransferase 3a (Dnmt3a) | |
| Concentration | 1.0 mg/ml |
| Background | DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, genetic imprinting, and X-chromosome inactivation. Hypermethylation of DNA has also been implicated in tumorigenesis through improper methylation of growth regulatory gene promoter regions. |
| Immunogen | Synthetic Peptide: D(86) L L P N G D L E K R S E P Q(100) C corresponding to amino acid residues 86-100 from human Dnmt3a. Remarks: SP5328P immunizing peptide (SP5328CP) is available for use in Neutralization and Control experiments |
| Format | State: Liquid purified IgG fraction. Purification: Epitope affinity chromatography. BufferSystem: PBS containing 1 mg/ml BSA as stabilizer and 0.05% sodium azide as preservative. |
| Applications | Western Blot: 2.0 µg/ml, detects an ~120 kDa protein representing Dnmt3a from P19 cell nuclear extracts. |
| Specificity | SP5328P detects DNA methyltransferase 3a (Dnmt3a) from human and mouse tissues and cells as well as recombinant human Dnmt3a.
This antibody does not detect full length recombinant human Dnmt3b or Dnmt1. |
| Storage | Store the antibody at -20°C.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. J. Biol. Chem., Vol 277: 11735-11745, Mar 2002
2. Cell 99(3):247-257, 1999. 3. Proc. Nat. Acad. Sci. USA 97(10):5237-5242, 2000. |
| Pictures | Figure 1. Western blot of Dnmt3a on P19 cell nuclear extract using SP5328P antibody. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 170,00 € | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160,00 € | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160,00 € | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / 170,00 € | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170,00 € | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 200,00 € | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 320,00 € | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 320,00 € | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / 320,00 € | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 320,00 € | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / 320,00 € | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 € | |||||
Click here to see all secondary antibodies for 'SP5328P DNA Methyltransferase 3a (Dnmt3a)'.
