SP5262P Cannabinoid Receptor 1 / CNR1 antibody
see related secondary antibodiessee all 25 Cannabinoid Receptor 1 / CNR1 products
0.1 ml / US$ 455
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Cannabinoid Receptor 1 / CNR1
Synonyms
CB1, CB-R, CANN6, CNR, ,
Product review
Please read our product review about Cannabinoid Receptor 1 / CNR1 : Antibody Panel to Cannabinoid Receptors.
Product Description
Rabbit anti Cannabinoid Receptor 1 / CNR1 , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Amphibian ( Amph ), Chicken ( Chk ), Fish ( Fish ), Human ( Hu ), Mouse ( Ms ), Prim ( Prim ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP5262P |
| Swiss Prot. No. | P21554 |
| Quantity | 0.1 ml |
| Price | US$ 455 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP5262P.pdf |
Datasheet Extract
| Concentration | 3.3 mg/ml |
| Background | Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels.
CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina. |
| Immunogen | A fusion protein containing the first 77 amino acid residues from rat CB1 Swiss Num.: P21554 |
| Format | State: Liquid Ig fraction Purification: Affinity chromatography BufferSystem: PBS containing 50% Glycerol, 1 mg/ml BSA and 0.05% sodium azide as preservative |
| Applications | FACS.
Immunohistochemistry on paraffin sections. Immunocytochemistry (1/1,000, results in intense, punctate staining along processes, with little staining over cell bodies in living or fixed cultured hippocampal neurons). Western Blot (detects an ~60 kDa protein representing CB1 and less intense bands of ~23 kDa, ~72 kDa, and ~180 kDa from rat brain homogenate). |
| Specificity | This antibody detects cannabinoid receptor 1 (CB1). Species: Human, rat, monkey, mouse, chicken, salamander, and goldfish. |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| References | Biochem. Journal 25 Jan. 2005 manuscript BJ0041682.
JCB, 163(3): 463-468, 2003. |
| Pictures | Figure 1 shows immunolocalization of cannibinoid receptor 1 in rat hippocampus. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP5262P Cannabinoid Receptor 1 / CNR1 '.
