SP5260P Cannabinoid receptor 1 antibody
see related secondary antibodiessee all 17 Cannabinoid receptor 1 products
0.1 ml / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Cannabinoid receptor 1 -
Synonyms
CB1 CB-R CANN6 CNR1 CNR
Product review
Please read our product review about Cannabinoid receptor 1: Antibody Panel to Cannabinoid Receptors.
Product Description
Rabbit anti Cannabinoid receptor 1 -, Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP5260P |
| Quantity | 0.1 ml |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP5260P.pdf |
Datasheet Extract
| Polyclonal Antibody to Cannabinoid Receptor 1 | |
| Concentration | 1.0 mg/ml |
| Background | Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions.
Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P/Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina. |
| Immunogen | A fusion protein containing the first 99 amino acid residues from human CB1 |
| Format | State: Liquid purified IgG fraction Purification: Affinity chromatography BufferSystem: PBS containing 50% glycerol, 1 mg/ml BSA and 0.05% sodium azide as preservative. |
| Applications | Western Blot (1/250): By Western blot, this antibody detects an ~52 kDa protein representing CB1 from rat brain homogenate.
Immunohistochemistry on frozen and paraffin embedded sections. Immunocytochemistry (1/1000): Immunocytochemical staining of CB1 in AtT20 cells transfected with the rat CB1 gene with SP5260P yields a pattern consistent with plasma membrane staining. |
| Specificity | This antibody detects cannabinoid receptor 1 (CB1) from human and rat tissues as well as transfected rat CB1. |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| References | Am J Physiol Gastrointest Liver Physiol, Vol 285: G566-G576, Aug 2003
J. Neuro. 25(10):2530-2536, 2005. |
| Pictures | Fig.1 shows immunolocalization of rat CB1 transfected into AtT20 cells using SP5260P. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 170,00 € | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160,00 € | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160,00 € | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / 170,00 € | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170,00 € | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 200,00 € | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 320,00 € | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 320,00 € | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / 320,00 € | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 320,00 € | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / 320,00 € | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 € | |||||
Click here to see all secondary antibodies for 'SP5260P Cannabinoid receptor 1'.
