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Immunohistochemical staining of kidney (renal tubules) using anti-AVPR2 antibody SP4536P

 

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SP4536P  Vasopressin V2 Receptor (C-term) antibody

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see all 9 Vasopressin V2 Receptor products
50 µg / no delivery possible
please contact the manufacturer

Quick Overview

Rabbit anti Vasopressin V2 Receptor (C-term) -

Synonyms

AVPR2 ADHR DIR DIR3 V2R

Product review
Please read our product review about Vasopressin V2 Receptor (C-term): - Antibody Panel to Vasopressin Receptors.

Product Description

Rabbit anti Vasopressin V2 Receptor (C-term) -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )

Properties

ApplicationsParaffin Sections ( P )
ReactivityHuman ( Hu )
PresentationAff - Purified
HostRabbit
Catalog NumberSP4536P
Quantity50 µg
Priceno delivery possible
DeliveryNot USA/Canada
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
SP4536P.pdf

Datasheet Extract

Polyclonal Antibody to Vasopressin V2 Receptor
Alternate namesADHR, DIR3, antidiuretic hormone receptor, arginine vasopressin receptor 2, renal-type arginine vasopressin receptor
Concentration1.0 mg/ml
BackgroundThe human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients.
The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.



ImmunogenSynthetic petide - KLH conjugated.
Epitope: C-terminal domain of human.

Genename: AVPR2
Remarks: The immunizing peptide shows 67 % identity (67 % similarity) with mouse and rat.
Format
State: Liquid Ig fraction
Purification: Peptide immunogen affinity column
BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide

ApplicationsImmunohistochemistry on paraffin embedded sections: 3-6 µg/ml.
Antigen retrieval:
Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
SpecificityThe antibody reacts with Vasopressin V2 Receptor (Family: GPCR, Subfamily: Vasopressin/oxytocin).

Species: Human.
Add. InformationThis product was originally produced by MBL International.
StorageStore the antibody at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch.
PicturesImmunohistochemical staining of kidney (renal tubules) using anti-AVPR2 antibody SP4536P



12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / 170,00 €
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / 160,00 €
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / 160,00 €
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / 170,00 €
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / 170,00 €
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / 200,00 €
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / 320,00 €
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / 320,00 €
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / 320,00 €
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / 320,00 €
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / 320,00 €
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / 330,00 €
   

Click here to see all secondary antibodies for 'SP4536P Vasopressin V2 Receptor (C-term)'.