SP4535P Vasopressin V2 Receptor / AVPR V2 (Cytoplasm. Dom.) antibody
see related secondary antibodiessee all 10 Vasopressin V2 Receptor / AVPR V2 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti Vasopressin V2 Receptor / AVPR V2 (Cytoplasm. Dom.) -
Synonyms
ADHR, DIR, DIR3, V2R, AVPRV2, , Renal-type arginine vasopressin receptor, Antidiuretic hormone receptor
Product review
Please read our product review about Vasopressin V2 Receptor / AVPR V2 (Cytoplasm. Dom.): - Antibody Panel to Vasopressin Receptors.
Product Description
Rabbit anti Vasopressin V2 Receptor / AVPR V2 (Cytoplasm. Dom.) -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4535P |
| Swiss Prot. No. | P30518 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4535P.pdf |
Datasheet Extract
| Polyclonal Antibody to Vasopressin V2 Receptor | |
| Alternate names | DI1, DIR, DIR3, MGC126533, MGC138386, NDI, V2R, ADHR, antidiuretic hormone receptor, arginine vasopressin receptor 2, arginine vasopressin receptor type ii, avp2r, avpr2, renal-type arginine vasopressin receptor, type 2 vasopressin receptor, v2 receptor, v2 vasopressin receptor, V2-renal V2R, v2r, vasopressin receptor type 2, vasopressin renal-type receptor, vasopressin type 2 receptor, vasopressin type II receptor |
| Concentration | 1 mg/ml |
| Background | The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients.
The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 3rd cytoplasmic domain of human Genename: AVPR2 Swiss Num.: P30518 Remarks: The immunizing peptide shows 100 % identity (100 % similarity) with mouse and 100 % identity (100 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry on paraffin embedded sections: 26 µg/ml
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts to Vasopressin V2 Receptor (AVPR2)
(Family: GPCR, Subfamily: Vasopressin/oxytocin) Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Kidney (Renal tubules) using anti- AVPR2 antibody SP4535P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||