SP4041P 5-HT1B / HTR1B antibody
see related secondary antibodiessee all 12 5-HT1B / HTR1B products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti 5-HT1B / HTR1B
Synonyms
5-Hydroxytryptamine Receptor 1B, Serotonin Receptor 1B, 5-HT-1D-beta, 5-HT-1B, S12, HTR1DB, , Serotonin 1D beta receptor, serotonin 5-ht-1b receptor, serotonin 5-ht-1d-beta receptor
Product review
Please read our product review about 5-HT1B / HTR1B : Antibodies to 5-hydroxytryptamine (Serotonin) Receptors.
Product Description
Rabbit anti 5-HT1B / HTR1B , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4041P |
| Swiss Prot. No. | P28222 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4041P.pdf |
Datasheet Extract
| Alternate names | HTR1D2, HTR1DB, S12, 5-HT-1B, 5-HT-1D-BETA, 5-HT1B, 5-HT1DB, 5-ht1b, 5-ht1b receptor, 5-ht1db, 5-hydroxytryptamine 1b receptor, 5-hydroxytryptamine-1d-beta receptor, htr1b, serotonin 1b receptor, serotonin 5-ht-1b receptor, serotonin 5-ht-1d-beta receptor |
| Concentration | 1.0 mg/ml |
| Background | 5-HT1B , a Serotonin Receptor, inhibits neurotransmitter release from neuronal terminals. Knockout mutant mice lacking this receptor exhibit decreased anxiety, increased aggression, and augmented alcohol and cocaine consumption compared to controls. 5-HT1B receptors have been found to control areas of the human brain involved in migraine pain, bipolar disorder, and obsessive compulsive disorder.
The 5-HT1B receptor has been reported to be expressed in a variety of neurons predominantly in the central nervous system. It has been suggested that Human 5-HT1B receptors are located somatodendritically on GABAergic and peptidergic caudate-putamen neurons which project to the substantia nigra and globus pallidus, where these receptors are presynaptic. 5-HT1B expression has also been seen in heart, blood vessels, and eye. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 3rd cytoplasmic domain of human Genename: HTR1B Swiss Num.: P28222 Remarks: The immunizing peptide shows 100 % identity (100 % similarity) with mouse. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry with formalin fixed paraffin embedded tissues (7 µg/ml).
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts with 5-HT1B receptor (family: GPCR, subfamily: Serotonin). Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Vascular smooth muscle using anti- HTR1B antibody SP4041P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4041P 5-HT1B / HTR1B '.
