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SP2168P  B-Cell Receptor-associated Protein 31 antibody

see related secondary antibodies
see all 15 B-Cell Receptor-associated Protein 31 products
0.1 mg / US$ 385
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Rabbit anti B-Cell Receptor-associated Protein 31

Synonyms

Protein CDM, BAP31, BCAP31, DXS1357E, BCR-associated protein Bap31, p28 Bap31, 6C6-AG tumor-associated antigen

Product Description

Rabbit anti B-Cell Receptor-associated Protein 31 , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms ), Rat ( Rt )
PresentationAff - Purified
HostRabbit
Catalog NumberSP2168P
Swiss Prot. No.P51572
Quantity0.1 mg
PriceUS$ 385
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
SP2168P.pdf

Datasheet Extract

Concentration1.0 mg/ml
BackgroundBAP31 is a 28 kDa conserved type III integral membrane protein of the Endoplasmic Reticulum (ER), containing two caspase cleavage sites within its cytosolic domain.
BAP31 appears to be a multi-functional ER-associated transport protein which was originally identified through its association with membrane IgD in B lymphocytes. Several proteins have since been shown to associate with BAP31, including the Beta2 integrin receptor CD11b/CD18, and nonmuscle gamma-actin and myosin B heavy chain. BAP31 has become a focus area for apoptosis studies due to its association with Bcl-2 and cleavage by initiator caspases including caspase 1 and 8. Cleavage of BAP31 generates a membrane-integrated p20 fragment which is itself a potent inducer of apoptosis when expressed ectopically.
ImmunogenA 17 amino acid peptide located near human BAP31 carboxy-terminus
Swiss Num.: P51572
Format
State: Liquid Ig fraction
Purification: Affinity chromatography
BufferSystem: Phosphate buffered saline, 0.02 % Sodium Azide (NaN3)
ApplicationsWestern blot (0.5 µg/ml).
SpecificityThis recognises an epitope within the C-terminal region (CT) of BAP31 (B cell receptor-associated protein 31).
Species: Human, Mouse, Rat.
StorageStore the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.
References1. Kim, K-M. et al. (1994) Two new proteins preferentially associated with membrane immunoglobulin D. EMBO J. 13: 3793-3800.
2. Ng, F. W. H. et al. (1997) p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the Endoplasmic Reticulum. J. Cell Biol. 139: 327-338.
3. Ducret, A. et al. (2003) The resident endoplasmic reticulum protein, BAP31, associates with gamma-actin and myosin B heavy chain. Eur. J. Biochem. 270: 342-349.
4. Zen, K. et al. (2004) Association of BAP31 with CD11b/CD18. J. Biol. Chem. 279: 44924-44930.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'SP2168P B-Cell Receptor-associated Protein 31'.