Acris Antibodies Logo

Antibodies and related products for scientific research: primary antibodies: 81.277, secondary ab: 1.977, proteins: 20.628, kits: 265, other products: 2.216

No staining picture available ...

 

Zoom Out
Zoom In

SP1227  Presenilin 1 / PS1 / PSEN1 antibody

see related secondary antibodies
see all 30 Presenilin 1 / PS1 / PSEN1 products
0.1 ml / US$ 485
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Goat anti Presenilin 1 / PS1 / PSEN1

Synonyms

Presenilin-1, PS-1, Protein S182, AD3, PSNL1, , Alzheimer disease 3

Product review
Please read our product review about Presenilin 1 / PS1 / PSEN1 : Antibody Panel to Presenilin 1 + 2.

Product Description

Goat anti Presenilin 1 / PS1 / PSEN1 , Presentation: Serum. Product is tested for Frozen sections ( C ), Enzyme Immunoassay ( E ), Paraffin Sections ( P )

Properties

ApplicationsFrozen sections ( C ), Enzyme Immunoassay ( E ), Paraffin Sections ( P )
ReactivityHuman ( Hu )
PresentationSerum
HostGoat
Catalog NumberSP1227
Swiss Prot. No.P49768
Quantity0.1 ml
PriceUS$ 485
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
SP1227.pdf

Datasheet Extract

BackgroundPresenilin-1 is a protein that has been linked with an early onset form on Alzheimers disease. Presenilin-1 is a membrane protein whose function is, as yet, undetermined.
ImmunogenN-terminus peptide (amino acids 14-33) of presenilin-1.
Swiss Num.: P49768
Format
State: Liquid serum
BufferSystem: Containing 0.09% Sodium Azide
ApplicationsELISA.
Western Blot.
Immunohistochemistry on frozen sections: 1:1000.
Immunohistochemistry on paraffin sections: 1:100; this product does not require protein digestion pre-treatment of paraffin sections; this product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Recommended Positive Control: Brain.
SpecificityThis antibody recognises presenilin-1.
Species: Human.
StorageStore the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Sherrington, R. et al. (1995) Cloning of a gene bearing missense mutations in early onset familial Alzheimers disease. Nature 357: 754-760.
2. Kovacs, D.M. et al. (1996) Alzheimer - associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med 2: 224-229.
3. Murphy, G.M. et al. (1996) Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimers disease. Am. J. Pathol. 149: 1839-1846.
4. Uchihara, T. et al. (1996) Widespread immunoreactivity of presenilin in neurons of normal and Alzheimers disease brains: double labelling immunohistochemical study. Acta. Neuropathol. 92: 325-330.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1317B Goat IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 295
   
R1317F Goat IgG (H&L)  
  Rabbit FITC   2 mg / US$ 295
   
R1317T Goat IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 295
   
R1317TR Goat IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1317HRP Goat IgG (H&L)  
  Rabbit HRP   2 mg / US$ 305
   
R1317AP Goat IgG (H&L)  
  Rabbit AP   1 mg / US$ 315
   
R1435C2 Goat IgG (H&L) multi-species ads.  
  Donkey Cy2   1 mg / US$ 445
   
R1435C3 Goat IgG (H&L) multi-species ads.  
  Donkey Cy3   1 mg / US$ 445
   
R1435C35 Goat IgG (H&L) multi-species ads.  
  Donkey Cy3.5   1 mg / US$ 445
   
R1435C5 Goat IgG (H&L) multi-species ads.  
  Donkey Cy5   1 mg / US$ 465
   
R1435C55 Goat IgG (H&L) multi-species ads.  
  Donkey Cy5.5   1 mg / US$ 445
   
R1416R Goat IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'SP1227 Presenilin 1 / PS1 / PSEN1 '.