SM6003 CD305 / LAIR-1 antibody
see related secondary antibodiessee all 20 CD305 / LAIR-1 products
0.1 ml / US$ 405
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti CD305 / LAIR-1 lc12
Synonyms
hLAIR1, LAIR1, , , Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin-like receptor 1, NK Cell Marker
Product review
Please read our product review about CD305 / LAIR-1 : NK-Cell Markers.
Product Description
Mouse anti CD305 / LAIR-1 lc12, Presentation: Purified. Product is tested for Enzyme Immunoassay ( E ), Flow cytometry ( F ), Western blot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Flow cytometry ( F ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | lc12 |
| Catalog Number | SM6003 |
| Swiss Prot. No. | Q6GTX8 |
| Quantity | 0.1 ml |
| Price | US$ 405 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SM6003.pdf |
Datasheet Extract
| Concentration | 1.0 mg/ml |
| Background | LAIR-1 is a member of the leukocyte-associated Ig like receptor family. The LAIR-1 is a transmembrane glycoprotein (~32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells (1,2). LAIR-1 recruits SHP-1 and SHP-2 tyrosine phosphatases upon activation, and cross-linking of the LAIR-1 molecule on NK cells results in strong inhibition of NK cell-mediated cytotoxicity. |
| Immunogen | Recombinant human LAIR-1 protein Swiss Num.: Q6GTX8 |
| Format | State: Liquid Ig fraction Purification: Protein G affinity chromatography, 0.2 µm filtered BufferSystem: phosphate buffered saline, pH 7.4 |
| Applications | Flow cytometry.
ELISA. Western blot. |
| Specificity | Reacts with extracellular domain of the LAIR-1.
Does not react with KIR2DL1, KIR2DL3 and KIR2DS4 in ELISA or Western blot. Species: Human. |
| Add. Information | The antibody has been tested by immunofluorescent staining with flow cytometric analysis and by Western blot analysis to assure specificity and reactivity (1). * Note: this product is routinely tested on peripheral blood mononuclear cells (PBMCs) or natural killer(NK) cells. The histogram is an example of the expected reactivity. |
| Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| References | 1. Meyaard L, Adema GJ, Chang C, Woollatt E, Sutherland GR, Lanier LL, Phillips JH. 1997. LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 7: 283-290.
2. Meyaard L, Hurenkamp J, Clevers H, Lanier LL, Phillips JH. 1999. Leukocyte-associated Ig-like receptor-1 functions as an inhibitory receptor on cytotoxic T cells. J. Immunol. 162: 5800-5804. |
| Pictures | Profile of LAIR-1 positive PBMC cells analyzed by flow cytometry. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SM6003 CD305 / LAIR-1 '.
