SM5139 B-Cell Receptor-associated Protein 31 antibody
see related secondary antibodiessee all 15 B-Cell Receptor-associated Protein 31 products
0.1 ml / US$ 455
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rat anti B-Cell Receptor-associated Protein 31 CC-4
Synonyms
Protein CDM, BAP31, BCAP31, DXS1357E, BCR-associated protein Bap31, p28 Bap31, 6C6-AG tumor-associated antigen
Product Description
Rat anti B-Cell Receptor-associated Protein 31 CC-4, Presentation: Ascites. Product is tested for Frozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Monkey ( Mky ), Bovine ( Bov ), Hamster ( Hst ) |
| Presentation | Ascites |
| Host | Rat |
| Isotype | IgG2a |
| Clone | CC-4 |
| Catalog Number | SM5139 |
| Swiss Prot. No. | P51572 |
| Quantity | 0.1 ml |
| Price | US$ 455 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SM5139.pdf |
Datasheet Extract
| Alternate names | B-Cell Receptor Associated Protein, 31-kDa |
| Background | BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein. In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis. |
| Immunogen | Amino acid residues 123-229 of human BAP31. Swiss Num.: P51572 Remarks: SM5139 antigen is solubilized protein from human neuroendocrine cell line IMR-32, followed by an extract of the small lung human carcinoma cell line SCC-9. SM5139 binds to a more proximal region of BAP31 (amino acids 123-229). This sequence is conserved in non-human primate, bovine and hamster species. |
| Format | State: Liquid ascites in 0.02% sodium azide as preservative. |
| Applications | Immunofluorescence: 1/200-1/6400.
Immunohistochemistry: 1/200-1/6400. Western Blot: 1/1500-1/6000, detects a 28-kDa protein corresponding to human BAP31. |
| Specificity | SM5139 detects BAP31 from human, non-human primate, bovine and hamster samples.
SM5139 binds to a more proximal region of BAP31 (amino acids 123-229). |
| Storage | Store the antibody at -20°C.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. JBC 279(43):44924-44930, 2004.
2. JBC (2005) Manuscript M509522200v1. |
| Pictures | Figure 1 shows a Western blot of BAP31 using SM5139. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1371B | Rat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1371F | Rat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1371T | Rat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1371TR | Rat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1371HRP | Rat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1371AP | Rat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 335 | |||||
| R1439C2 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1439C3 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1439C35 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1439C5 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1439C55 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1413R | Rat IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Ms, Rb, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1428R | Rat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
| R1415R | Rat IgG F(ab')2 F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SM5139 B-Cell Receptor-associated Protein 31'.
