SM2227R CD335 (NKp46) antibody
see related secondary antibodiessee all 5 CD335 products
100 Tests / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti CD335 (NKp46) AKS1
Synonyms
NK Cell Marker
Product Description
Mouse anti CD335 (NKp46) AKS1. Product is tested for Flow cytometry ( F )
Properties
| Applications | Flow cytometry ( F ) |
| Reactivity | Bovine ( Bov ) |
| Presentation | PE |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | AKS1 |
| Catalog Number | SM2227R |
| Quantity | 100 Tests |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SM2227R.pdf |
Datasheet Extract
| Monoclonal Antibody to Bovine CD335 // RPE | |
| Alternate names | NKp46; Natural cytotoxicity triggering receptor 1 |
| Concentration | 0.1 mg/ml |
| Background | CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.
|
| Immunogen | Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line. |
| Format | State: Lyophilised purified IgG Purification: Affinity chromatography on Protein G BufferSystem: PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: R. Phycoerythrin (RPE) Reconstitution: Restore with 1 ml distilled water |
| Applications | Flow Cytometry: neat- 1/5; use 10 µl of the suggested working dilution to label 106 cells in 100 µl. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. |
| Specificity | This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells. Species: Bovine. |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch. |
| References | 1. Storset, A.K. et al. (2003) Natural killer cell receptors in cattle: a bovine killer cell immunoglobulin- like receptor multigene family contains members with divergent signaling motifs. Eur. J. Immunol. 33:980-990.
2. Storset, A.K. et al. (2004) NKp46 defines a subset of bovine leukocytes with natural killer characteristics. Eur. J. Immunol. 34:669-676. 3. Kulberg, S. et al. (2004) Reference values for relative numbers of natural killer cells in cattle blood. Dev. Comp. Immunol. 28:941-948. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 180,00 € | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 160,00 € | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / 160,00 € | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170,00 € | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 190,00 € | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 200,00 € | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 320,00 € | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 320,00 € | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / 320,00 € | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 320,00 € | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / 320,00 € | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / 330,00 € | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / 330,00 € | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 € | |||||
Click here to see all secondary antibodies for 'SM2227R CD335 (NKp46)'.
