SM2227P CD335 / NKp46 antibody
see related secondary antibodiessee all 10 CD335 / NKp46 products
0.25 mg / US$ 495
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti CD335 / NKp46 AKS1
Synonyms
NK-p46, hNKp46, NCR1, LY94, , , Natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NK cell-activating receptor, Lymphocyte antigen 94 homolog, NK Cell Marker
Product review
Please read our product review about CD335 / NKp46 : NK-Cell Markers.
Product Description
Mouse anti CD335 / NKp46 AKS1, Presentation: Purified. Product is tested for Flow cytometry ( F ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Western blot / Immunoblot ( WB ) |
| Reactivity | Bovine ( Bov ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | AKS1 |
| Catalog Number | SM2227P |
| Swiss Prot. No. | Q863H2 |
| Quantity | 0.25 mg |
| Price | US$ 495 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SM2227P.pdf |
Datasheet Extract
| Alternate names | NKp46; Natural cytotoxicity triggering receptor 1 |
| Concentration | 1.0 mg/ml |
| Background | CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells. The bovine homologue is expressed on bovine NK cells and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.
|
| Immunogen | Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line. Swiss Num.: Q863H2 |
| Format | State: Liquid purified IgG Purification: Affinity chromatography on Protein G BufferSystem: PBS, pH7.4 containing 0.09% Sodium Azide |
| Applications | Flow cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Western Blot. |
| Specificity | This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells. Species: Bovine. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Storset, A.K. et al. (2003) Natural killer cell receptors in cattle: a bovine killer cell immunoglobulin-like receptor multigene family contains members with divergent signaling motifs. Eur. J. Immunol. 33:980-990.
2. Storset, A.K. et al. (2004) NKp46 defines a subset of bovine leukocytes with natural killer characteristics. Eur. J. Immunol. 34:669-676. 3. Kulberg, S. et al. (2004) Reference values for relative numbers of natural killer cells in cattle blood. Dev. Comp. Immunol. 28:941-948. 4. Sivori, S. et al. (1997) p46, a novel natural killer cell-specific surface molecule that mediates cell activation. J. Exp. Med. 186:1129-1136. |
| Pictures | Staining of bovine peripheral blood lymphocytes with MOUSE ANTI BOVINE CD335 (SM2227P). |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SM2227P CD335 / NKp46 '.
