SM2048R CD305 / LAIR-1 antibody
see related secondary antibodiessee all 20 CD305 / LAIR-1 products
100 Tests / US$ 555
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti CD305 / LAIR-1 NKTA255
Synonyms
hLAIR1, LAIR1, , , Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin-like receptor 1, NK Cell Marker
Product review
Please read our product review about CD305 / LAIR-1 : NK-Cell Markers.
Product Description
Mouse anti CD305 / LAIR-1 NKTA255. Product is tested for Flow cytometry ( F )
Properties
| Applications | Flow cytometry ( F ) |
| Reactivity | Human ( Hu ) |
| Presentation | PE |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | NKTA255 |
| Catalog Number | SM2048R |
| Swiss Prot. No. | Q6GTX8 |
| Quantity | 100 Tests |
| Price | US$ 555 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SM2048R.pdf |
Datasheet Extract
| Alternate names | CD305 |
| Concentration | 0.1 mg/ml |
| Background | LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes. |
| Immunogen | NK cells lines B12.100 and AM.25. Spleen cells from immunised mice were fused with cells of the P3U1 myeloma cell line. Swiss Num.: Q6GTX8 |
| Format | State: Lyophilized purified IgG Purification: Affinity chromatography on Protein G BufferSystem: PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: R. Phycoerythrin (RPE) Reconstitution: Restore with 1.0 ml distilled water |
| Applications | Flow cytometry. |
| Specificity | This antibody recognises leukocyte-associated Ig-like receptor-1 (LAIR-1). Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules. We recommend the use of SM2048A for this purpose. Species: Human. |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch. |
| References | 1. Poggi, A. et al. (1995) p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans. Eur. J. Immunol. 25: 369 - 376.
2. Zocchi, M. R. et al. (2001) Leukocyte-associated Ig-like receptor-1 prevents granulocyte-monocyte colony stimulating factor dependent proliferation and Akt1/PKB alpha activation in primary acute myeloid leukemia cells. Eur. J. Immunol. 31: 3667 - 3675. 3. Poggi, A. et al. (2000) Engagement of the leukocyte-associated Ig-like receptor-1 induces programmed cell death and prevents nuclear translocation in human myeloid leukemias. Eur. J. Immunol. 30: 2751 - 2758. |
| Pictures | Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD305:RPE (SM2048R). |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SM2048R CD305 / LAIR-1 '.
