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PA268X  Macrophage Colony Stimulating Factor (M-CSF) antigen


see all 76 Macrophage Colony Stimulating Factor products
10 µg / US$ 355
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Mouse Macrophage Colony Stimulating Factor (M-CSF)

Synonyms

MCSF

Product Description

Mouse Macrophage Colony Stimulating Factor (M-CSF) ;Is tested for Flow cytometry (F)

Properties

SpeciesMouse
Purity>98%
SourceE. coli
Molecular Weight18.2 kD
Catalog NumberPA268X
Quantity10 µg
PriceUS$ 355
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
PA268X.pdf

Datasheet Extract

Recombinant Murine M-CSF
Alternate namesMacrophage Colony Stimulating Factor (MCSF)
BackgroundM-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells.
SourceE.coli
Format
State: Lyophilized purified fraction (>98% pure by SDS-PAGE) with no additives.
Endotoxinlevel: < 0.1 ng per µg (1EU/µg)
Reconstitution: Restore in water to a concentration of 0.1-1.0 mg/ml.
This solution can then be diluted into other aqueous buffers and stored at 2-8°C for 1 week or
-20°C for future use.
DescriptionRecombinant murine M-CSF is a 36.4 kDa homodimeric protein containing two 156 amino acid polypeptide subunits.
AASequence: MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of M-NFS-60 cells is < 1.0 ng/ml.
Specific Activity: > 1 x 10e6 units/mg
Molecular weight: 36.4 kDa
Add. InformationCentrifuge the vial prior to opening!
StorageStore the lyophilized protein at -20°C.
Reconstituted M-CSF should be stored in working aliquots at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.