PA185X BLC / CXCL13 antigen
see all 18 BLC / CXCL13 products
20 µg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse BLC / CXCL13
Synonyms
SCYB13 B Lymphocyte Chemoattractant C-X-C motif chemokine 13, Small-inducible cytokine B13, CXC chemokine BLC
Product Description
Mouse BLC / CXCL13 ;Is tested for Flow cytometry (F)
Properties
| Presentation | Purified |
| Species | Mouse |
| Purity | >98% |
| Source | E. coli |
| Catalog Number | PA185X |
| Swiss Prot. No. | O55038 |
| Quantity | 20 µg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA185X.pdf |
Datasheet Extract
| Recombinant Murine BLC/BCA (CXCL13) | |
| Alternate names | B-Cell Attracting Chemokine 1, CXCL13, BLR1 Ligand
|
| Background | BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. |
| Immunogen | Swiss Num.: O55038 |
| Source | E. coli |
| Format | State: Lyophilized purified fraction (>98% pure by SDS-PAGE and HPLC analyses) without additives. Endotoxinlevel: < 0.1 ng per µg (1EU/µg) Reconstitution: Restore in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 2-8°C for 1 week or -20°C for future use. |
| Description | Recombinant murine BLC is a protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. AASequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA. Biological Activity: Determined by its ability to chemoattract murine B cells using a concentration of 10.0-100.0 ng/ml. Molecular weight: 9.8 kDa |
| Add. Information | Centrifuge the vial prior to opening! |
| Storage | Store the lyophilized protein at -20°C.
Reconstituted BLC should be stored in working aliquots with a carrier protein at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Al-Alwan, M. Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses The Journal of Immunology, 2007, 178(12):7859-7867.
2. Ha SA, Regulation of B1 cell migration by signals through Toll-like receptors J Exp Med., 2006, 203(11):2541-2550. 3. Rubtsov A Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response Immunity, 2005, 23(5):527-538. 4. Edward P. Bowman The Intestinal Chemokine Thymus-expressed Chemokine (CCL25) Attracts IgA Antibody-secreting Cells J. Exp. Med., 2002, Vol: 195 (2) pp. 269-275. |
