PA1273 UBC9 (Ubiquitin-conjugating enzyme) antigen
see all 7 UBC9 products
10 µg / US$ 225
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Human UBC9 (Ubiquitin-conjugating enzyme)
Product Description
Human UBC9 (Ubiquitin-conjugating enzyme)
Properties
| Presentation | Purified |
| Species | Human |
| Purity | >98% |
| Source | E. coli |
| Molecular Weight | 23 kD |
| Catalog Number | PA1273 |
| Quantity | 10 µg |
| Price | US$ 225 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA1273.pdf |
Datasheet Extract
| Recombinant Human UBC9//(Ubiquitin-conjugating enzyme) | |
| Alternate names | SUMO-protein ligase, C358B7.1 |
| Concentration | 1 mg/ml (prior to lyophil.) |
| Background | Human Ubquitin Conjugating Enzyme 9 (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumolyation, and may play a role in substrate recognition. Ubc9 can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, IκBα, and PML without the requirement of an E3 ligase. |
| Source | E. coli |
| Format | State: Sterile Filtered white lyophilized powder Purity: Purified by proprietary chromatographic techniques, 0.2 ?m filtered, purity is greater than 95.0% as determined by: (a) Analysis by RP-HPLC (b) Analysis by SDS-PAGE. BufferSystem: 1 X PBS and 1mM DTT, pH 7.5 Reconstitution: Restore in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Description | Recombinant Human Ubiquitin Conjugating Enzyme 9 is a protein containing 171 amino acids. The protein contains 6x His tag.
AASequence: MHHHHHHAMGTLNMSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMN WECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPS GTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQN RVEYEKRVRAQAKKFAPS Molecular weight: 19.5 kDa |
| Storage | Lyophilized product although stable at room temperature for 3 weeks, should be stored desiccated below -18 °C. Upon reconstitution it should be stored at 2 - 8 °C between 2 - 7 days and for future use below -18 °C. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA).
Please avoid freeze-thaw cycles. Shelf life: One year from despatch. |