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PA1259  Histidyl-tRNA synthetase antigen


see all 5 Histidyl-tRNA synthetase products
0.1 mg / US$ 345
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human Histidyl-tRNA synthetase

Synonyms

HARS HRS EC 6.1.1.21 Histidine-tRNA ligase HisRS Jo1 Jo-1

Product Description

Human Histidyl-tRNA synthetase ;Is tested for Flow cytometry (F)

Properties

PresentationPurified
SpeciesHuman
Purity>98%
SourceE. coli
Molecular Weight55 kD
Catalog NumberPA1259
Swiss Prot. No.P12081
Quantity0.1 mg
PriceUS$ 345
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
PA1259.pdf

Datasheet Extract

Recombinant Human Histidyl-tRNA Synthetase
Alternate namesHistidyl-tRNA synthetase, EC 6.1.1.21, Histidine-tRNA ligase, HisRS, HRS, FLJ20491, JO-1
Concentration1.2 mg/ml
BackgroundAminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Immunogen
Swiss Num.: P12081
SourceE. coli
Format
State: Sterile filtered clear solution
Purity: Purified by proprietary chromatographic techniques, purity is greater than 90.0% as determined by both:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE
BufferSystem: 150 mM NaCl and 10 mM sodium phosphate containing 0.1 % NaN3
(pH 7.2)
DescriptionRecombinant Human Histidyl-tRNA Synthetase is a single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa.
Molecular weight: 55 kDa
StorageProduct is stable at 2 - 8 °C for 3 weeks, should be stored desiccated below -18 °C.
Please avoid freeze thaw cycles.
Shelf life: One year from despatch.