PA1231XC Mitogen-activated protein kinase 10 antigen
see all 6 Mitogen-activated protein kinase 10 products
1 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Human Mitogen-activated protein kinase 10
Synonyms
MAPK10 MAPK-10 JNK3 JNK3A PRKM10 JNK-3 Stress-activated protein kinase JNK3 c-Jun N-terminal kinase 3 MAP kinase p49 3F12
Product Description
Human Mitogen-activated protein kinase 10 ;Is tested for Flow cytometry (F)
Properties
| Presentation | Purified |
| Species | Human |
| Purity | >85% |
| Source | E. coli |
| Molecular Weight | 52 kD |
| Catalog Number | PA1231XC |
| Swiss Prot. No. | P53779 |
| Quantity | 1 mg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA1231XC.pdf |
Datasheet Extract
| Recombinant Human SHP-1 | |
| Alternate names | Tyrosine-protein phosphatase non-receptor type 6, EC 3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, Hematopoietic cell protein-tyrosine phosphatase, SH-PTP1, Protein-tyrosine phosphatase SHP-1, PTPN6, HCP, HCPH, SHP1, HPTP1C, SHP-1L |
| Concentration | 1,0 mg/ml |
| Background | SHP-1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. |
| Immunogen | Swiss Num.: P53779 |
| Source | Escherichia Coli |
| Format | State: Liquid purified protein (Sterile filtered colorless solution) Purity: Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE. BufferSystem: 25mM Tris-HCl, pH 7.5, 2mM b-mercaptoethanol, 1mM EDTA, 1mMDTT and 20%Glycerol |
| Description | SHP-1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain conjtaining 300 amino acids. The protein coding region of the catalytic domain of SHP-1 (amino acids 243-541). The catalytic domain of SHP-1 was overexpressed as insoluble protein aggregates (inclusion bodies). The recombinant SHP-1 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. Additional amino acid(Met) is attached at N-terminus.
AASequence: Mgfweefes lqkqevknlh qrlegqrpen kgknryknil pfdhsrvilq grdsnipgsdyinanyiknq llgpdenakt yiasqgclea tvndfwqmaw qensrvivmt trevekgrnkcvpywpevgm qraygpysvt ncgehdttey klrtlqvspl dngdlireiw hyqylswpdhgvpsepggvl sfldqinqrq eslphagpii vhcsagigrt gtiividmlm enistkgldcdidiqktiqm vraqrsgmvq teaqykfiyv aiaqfiettk kklevlqsqk gqeseygnity Specific Activity: 5,000 U/mg (One unit will hydrolyze 1nanomole of p-nitrophenylphosphatate per minute at pH 7.5 at 37°C using 10mM of substrate.) Molecular weight: 34.3 kDa |
| Storage | Store the protein undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Shelf life: one year from despatch. |
