PA025 Macrophage Chemotactic Protein-5 (MCP-5) antigen
see all 6 Macrophage Chemotactic Protein-5 products
5 µg / US$ 255
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse Macrophage Chemotactic Protein-5 (MCP-5)
Synonyms
MCP5 CCL12
Product Description
Mouse Macrophage Chemotactic Protein-5 (MCP-5) ;Is tested for Flow cytometry (F)
Properties
| Species | Mouse |
| Purity | >99% |
| Source | E. coli |
| Molecular Weight | 9.3 kD |
| Catalog Number | PA025 |
| Quantity | 5 µg |
| Price | US$ 255 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA025.pdf |
Datasheet Extract
| Recombinant Murine MCP-5 (CCL12) | |
| Alternate names | Monocyte Chemotactic Protein-5, CCL12
|
| Background | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. |
| Source | E.coli |
| Format | State: Lyophilized purified fraction (>98% pure by SDS-PAGE and HPLC analyses) without additives. Endotoxinlevel: < 0.1 ng per µg (1EU/µg) Reconstitution: Restore in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 2-8°C for 1 week or -20°C for future use. |
| Description | Recombinant murine MCP-5 is a protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. AASequence: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-50.0 ng/ml. Molecular weight: 9.3 kDa |
| Add. Information | Centrifuge the vial prior to opening! |
| Storage | Store the lyophilized protein at -20°C.
Reconstituted murine MCP-5 should be stored in working aliquots with a carrier protein at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Lim H.W., Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells. Journal of Immunology, 2006, 177(2):840-51.
2. Cesar Nombela-Arrieta Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing. Immunity, 2004, 21(3):429-41. 3. Sarafi MN., Murine Monocyte Chemoattractant Protein (MCP)-5: A Novel CC Chemokine That Is a Structural and Functional Homologue of Human MCP-1. J. Exp. Med. The Rockefeller University Pres., 1997, Volume 185. Pp.99-110. |
