NLS598 5-HT1B / HTR1B antibody
see related secondary antibodiessee all 12 5-HT1B / HTR1B products
0.05 ml / US$ 575 no delivery possible
Quick Overview
Rabbit anti 5-HT1B / HTR1B
Synonyms
5-Hydroxytryptamine Receptor 1B, Serotonin Receptor 1B, 5-HT-1D-beta, 5-HT-1B, S12, HTR1DB, , Serotonin 1D beta receptor, serotonin 5-ht-1b receptor, serotonin 5-ht-1d-beta receptor
Product review
Please read our product review about 5-HT1B / HTR1B : Antibodies to 5-hydroxytryptamine (Serotonin) Receptors.
Product Description
Rabbit anti 5-HT1B / HTR1B , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NLS598 |
| Swiss Prot. No. | P28222 |
| Quantity | 0.05 ml |
| Price | US$ 575 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-5-HT1B Receptor | |
| Alternate names | anti-5 HT1DB antibody, anti-5 hydroxytryptamine (serotonin) receptor 1B antibody, anti-HTR1B antibody, anti-HTR1D2 antibody, anti-HTR1DB antibody, anti-S12 antibody |
| Concentration | 1 mg/ml |
| Background | 5-HT1B (5-HT1D beta), a Serotonin Receptor, inhibits neurotransmitter release from neuronal terminals. Knockout mutant mice lacking this receptor exhibit decreased anxiety, increased aggression, and augmented alcohol and cocaine consumption compared to controls. 5-HT1B receptors have been found to control areas of the human brain involved in migraine pain, bipolar disorder, and obsessive compulsive disorder. The 5-HT1B receptor has been reported to be expressed in a variety of neurons predominantly in the central nervous system. It has been suggested that Human 5-HT1B receptors are located somatodendritically on GABAergic and peptidergic caudate-putamen neurons which project to the substantia nigra and globus pallidus, where these receptors are presynaptic. 5-HT1B expression has also been seen in heart, blood vessels, and eye. |
| Immunogen | Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop Swiss Num.: P28222 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: PBS |
| Applications | IHC-P |
| Specificity | Species: Human. There is 100 % rat identity and 100 % rat homology. There is 100 % mouse identity and 100 % mouse homology. |
| References | 1. Guilluy, C., Rolli-Derkinderen, M., Tharaux, P.-L., Melino, G., Pacaud, P., and Loirand, G. (2007) Transglutaminase-dependent RhoA Activation and Depletion by Serotonin in Vascular Smooth Muscle Cells, 282, 2918-2928. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NLS598 5-HT1B / HTR1B '.
