NLS1111 5-HT2B / HTR2B antibody
see related secondary antibodiessee all 9 5-HT2B / HTR2B products
0.05 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti 5-HT2B / HTR2B
Synonyms
5-hydroxytryptamine Receptor 2B, 5-HT-2B, Serotonin receptor 2B, , serotonin, 2B
Product review
Please read our product review about 5-HT2B / HTR2B : Antibodies to 5-hydroxytryptamine (Serotonin) Receptors.
Product Description
Rabbit anti 5-HT2B / HTR2B , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P ), Immunofluorescence ( IF )
Properties
| Applications | Paraffin Sections ( P ), Immunofluorescence ( IF ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NLS1111 |
| Swiss Prot. No. | P41595 |
| Quantity | 0.05 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-5-HT2B Receptor | |
| Alternate names | anti-5 hydroxytryptamine (serotonin) receptor 2B antibody, anti-5 hydroxytryptamine 2B receptor antibody, anti-5HT(2B) antibody, anti-5HT2F antibody, anti-Htr2b antibody, anti-NP75 protein antibody, anti-SEROTONIN 5HT2B RECEPTOR antibody, anti-Serotonin receptor 2B antibody, anti-Stomach fundus serotonin receptor antibody |
| Concentration | 1 mg/ml |
| Background | 5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood; mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation. Abnormal vascular proliferation causes an increase in pulmonary blood pressure, which is associated with an increase in 5-HT2B receptor, resulting in the development of pulmonary hypertension. It has also been reported that the 5-HT2B is involved in cell-cycle regulation via interaction with tyrosine kinase pathways. 5-HT2B receptors may have a role in the initiation of migraine headaches, and selective antagonists may prove therapeutic in migraine treatment. 5-HT2B receptor is expressed in many tissues including human liver, kidney, lung, heart, pancreas, spleen, brain, spinal cord, gastrointestinal tract, placenta, and coronary and pulmonary arteries. It has also been reported in embryonic mouse heart and spinal cord. ESTs have been isolated from heart/melanocyte/uterus, kidney, prostate, skin, and thyroid libraries. |
| Immunogen | Synthetic peptide [KLH conjugated] made to the 2nd extracellular loop Swiss Num.: P41595 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: PBS |
| Applications | IHC-P, ICC |
| Specificity | Species: Human. There is 73 % rat identity and 80 % rat homology. There is 80 % mouse identity and 93 % mouse homology. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NLS1111 5-HT2B / HTR2B '.
