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NB600-1096  EDG-2 / LPA1 antibody

see related secondary antibodies
see all 15 EDG-2 / LPA1 products
25 µg / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti EDG-2 / LPA1

Synonyms

EDG2, LPA-1, LPAR1, vzg1, MREC1.3, REC1.3, , Lysophospholipid receptor A1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor Edg-2

Product review
Please read our product review about EDG-2 / LPA1 : Antibodies to Endothelial Differentiation Gene Receptors (EDG-1,-2,-4,-5,-6,-7 and -8).

Product Description

Rabbit anti EDG-2 / LPA1 , Presentation: Ig Fraction. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Rat ( Rt )
PresentationIg Fraction
HostRabbit
Catalog NumberNB600-1096
Swiss Prot. No.Q92633
Quantity25 µg
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/p ...

Datasheet Extract

Rabbit Polyclonal anti-EDG2
Alternate namesanti-EDG 2 antibody, anti-Endothelial Cell Differentiation Gene-2 antibody, anti-Endothelial Differentiation Lysophosphatidic Acid G Protein Coupled Receptor 2 antibody, anti-G10 protein homolog antibody, anti-GPCR26 antibody, anti-LPA receptor 1 antibody, anti-LPA1 antibody, anti-LPAR 1 antibody, anti-LPAR1 antibody, anti-Lysophosphatidic acid receptor EDG2 antibody, anti-MREC1.3 antibody, anti-REC1.3 antibody, anti-Ventricular zone gene 1 antibody, anti-VZG1 antibody
Concentration1 mg/ml
BackgroundEDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several proteins not used within 12 hours. Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate and uterus libraries.
ImmunogenSynthetic peptide: CQRSENPTGPTEGSDRS, corresponding to C-term amino acids 328-344 of Human EDG2.
Swiss Num.: Q92633
Format
Purification: IgG purified
Purity: IgG purified
BufferSystem: phosphate buffered saline, pH 7.4
ApplicationsWestern Blot
Specificity
Species: Cross-reacts with Human and Rat.
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
ReferencesGeneral / background references:Goetzl EJ & Gräler MH Sphingosine 1-phosphate and its type 1 G protein-coupled receptor: trophic support and functional regulation of T Lymphocytes. J Leukoc Biol : (2004). Fukushima N et al. A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid. Proc Natl Acad Sci U S A 95:6151-6 (1998).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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