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NB500-491  Death domain-associated protein 6 antibody

see related secondary antibodies
see all 23 Death domain-associated protein 6 products
0.1 mg / US$ 465 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti Death domain-associated protein 6 DAXX-01

Synonyms

anti-BING2 antibody, anti-DAP6 antibody, Fas death domain-associated protein

Product Description

Mouse anti Death domain-associated protein 6 DAXX-01, Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationAff - Purified
HostMouse
IsotypeIgG1
CloneDAXX-01
Catalog NumberNB500-491
Swiss Prot. No.O35613
Quantity0.1 mg
PriceUS$ 465 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Mouse Monoclonal anti-Daxx (DAXX-01)
Alternate namesanti-BING2 antibody, anti-DAP6 antibody
BackgroundApoptosis, or programmed cell death, occurs duringnormal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
ImmunogenRecombinant fragment, corresponding to amino acids 558-740 of Human Daxx. Produced in E. coli
Swiss Num.: O35613
Format
Purification: Affinity purified
Purity: Affinity purified
BufferSystem: Preservative: 15mM Sodium AzideConstituents: PBS. pH 7.4
ApplicationsICC, WB
Specificity
Species: Cross-reacts with Human.Not yet tested in other species.
ReferencesGeneral / background references:Yang X et al. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89:1067-76 (1997). Kiriakidou M et al. Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region. DNA Cell Biol 16:1289-98 (1997).

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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