NB400-132SS ABCG1 antibody
see related secondary antibodiessee all 10 ABCG1 products
0.025 ml / US$ 295 no delivery possible
Quick Overview
Rabbit anti ABCG1
Synonyms
anti-ABC8 antibody, anti-MGC34313 antibody, anti-WHITE1 antibody,
Product Description
Rabbit anti ABCG1 , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB400-132SS |
| Quantity | 0.025 ml |
| Price | US$ 295 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-ABCG1 **Sample Size** | |
| Alternate names | anti-ABC8 antibody, anti-MGC34313 antibody, anti-WHITE1 antibody |
| Concentration | 1 mg/ml |
| Background | ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1. |
| Immunogen | A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400). |
| Format | Purification: peptide affinity purified Purity: peptide affinity purified |
| Applications | IHC, WB |
| Specificity | Species: This antibody reacts with mouse and human protein. Other species have not been tested. There is 100%/100% identity/homology of the immunogen used for this production and the human protein sequence. There is 84%/89% for mouse and 78%/88% for rat. |
| References | 1. Avallone, R., Demers, A., Rodrigue-Way, A., Bujold, K., Harb, D., Anghel, S., Wahli, W., Marleau, S., Ong, H., and Tremblay, A. (2006) A Growth Hormone-Releasing Peptide that Binds Scavenger Receptor CD36 and Ghrelin Receptor Up-Regulates Sterol Transporters and Cholesterol Efflux in Macrophages through a Peroxisome Proliferator-Activated Receptor {gamma}-Dependent Pathway, 20, 3165-3178. 2. Li, T., Chen, W., and Chiang, J. Y. L. (2007) PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine, 48, 373-384. 3. Ranalletta, M., Wang, N., Han, S., Yvan-Charvet, L., Welch, C., and Tall, A. R. (2006) Decreased Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice Transplanted With Abcg1-/- Bone Marrow, 26, 2308-2315. 4. Tansley, G. H., Burgess, B. L., Bryan, M. T., Su, Y., Hirsch-Reinshagen, V., Pearce, J., Chan, J. Y., Wilkinson, A., Evans, J., Naus, K. E., McIsaac, S., Bromley, K., Song, W., Yang, H.-C., Wang, N., DeMattos, R. B., and Wellington, C. L. (2007) The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta -amyloid precursor protein, M600542-JLR600200. 5. Wang, M.-D., Kiss, R. S., Franklin, V., McBride, H. M., Whitman, S. C., and Marcel, Y. L. (2007) Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways, 48, 633-645. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB400-132SS ABCG1'.
