NB400-113 Scavenger Receptor Class B Type I (SR-BI) antibody
see related secondary antibodiessee all 3 Scavenger Receptor Class B Type I products
0.1 ml / US$ 465 no delivery possible
Quick Overview
Rabbit anti Scavenger Receptor Class B Type I (SR-BI)
Product Description
Rabbit anti Scavenger Receptor Class B Type I (SR-BI) , Presentation: Serum. Product is tested for Flow cytometry ( F ), Functional assay ( FN ), Immunoprecipitation ( IP )
Properties
| Applications | Flow cytometry ( F ), Functional assay ( FN ), Immunoprecipitation ( IP ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Serum |
| Host | Rabbit |
| Catalog Number | NB400-113 |
| Quantity | 0.1 ml |
| Price | US$ 465 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB400-113.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-SR-BI | |
| Alternate names | anti-SCARB1 antibody, anti-SR-B1 antibody, anti-SR-BI antibody, anti-Scavenger Receptor-BI antibody, anti-Scavenger Receptor-B1 antibody |
| Background | High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism.
In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. |
| Immunogen | Adenovirus encoding mSR-BI. |
| Format | Purification: Whole antisera Purity: Whole antisera |
| Applications | immunoprecipitation 1:100, BL 1:500-1000 |
| Specificity | Species: NB 400-113 reacts with mouse SR-BI. It can block human SR-BI/Cla-1 (tested in HepG2 cells). Other species have not been tested. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Gu, X., et al. Scavenger Receptor Class B, Type I-mediated [3H] cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor. The Journal of Biological Chemistry. 275 (39): 29993-30001, 2000. 1. Wustner, D. et al. Different transport routes for high density lipoprotein and its association free sterol in polarized hepatic cells. Journal of Lipid Research. 45: 427-437, 2004. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB400-113 Scavenger Receptor Class B Type I (SR-BI)'.
