NB400-104 Scavenger Receptor Class B Type I (SR-BI) antibody
see related secondary antibodiessee all 3 Scavenger Receptor Class B Type I products
0.1 ml / US$ 435 no delivery possible
Quick Overview
Rabbit anti Scavenger Receptor Class B Type I (SR-BI)
Synonyms
SRBI,
Product Description
Rabbit anti Scavenger Receptor Class B Type I (SR-BI) , Presentation: Purified. Product is tested for Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | NB400-104 |
| Quantity | 0.1 ml |
| Price | US$ 435 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB400-104.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-SR-BI | |
| Alternate names | anti-SCARB1 antibody; anti-SR-B1 antibody; anti-SR-BI antibody; anti-Scavenger Receptor-BI antibody; anti-Scavenger Receptor-B1 antibody; anti-HCLA 1 antibody, anti-SRBI antibody |
| Concentration | 3.0 mg/ml |
| Background | High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism.
In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. |
| Immunogen | A C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509). |
| Format | Purification: Affinity purified Purity: Affinity purified BufferSystem: Tris-citrate/phosphate [pH 7-8] buffer. |
| Applications | immunohistochemistry , immunoprecipitation , Western Blot 1:1000 -1:5000 |
| Specificity | Species: Reacts with mouse, rat, mink and hamster SR-BI and the long form of human CLA-I. |
| Storage | Store at 4C. Do not freeze. |
| References | 1. Hullinger, Thomas G., et al. PAK1 Inhibition of the Human SR-BI Promoter in Macrophages is Independent of the PAK1 Kinase Activity but Requires the GTPase Binding Domain. JBC Papers in Press.276(50): 46807-46814, 2001.
2. Witt, W., et al. Regulation by vitamin E of the scavenger receptor B1 in rat liver and HepG2 cells. Journal of Lipid Research. 41: 2009-2016, 2000. 3. Goti, D., et al. Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-Tocopherol in a porcine in vitro blood-brain barrier model. JBC Papers in Press. Published on May 24, 2002 as Manuscript M203989200. 4. Thomas-Moya, E., Gianotti, M., Proenza, A. M., and Llado, I. (2006) The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats, 47, 2042-2048. 5. Timmers, C., Sharma, N., Opavsky, R., Maiti, B., Wu, L., Wu, J., Orringer, D., Trikha, P., Saavedra, H. I., and Leone, G. (2006) E2f1-3 Control E2F-target Expression and Cellular Proliferation via a p53-dependent Negative Feedback Loop, MCB.02147-02105. 6. Timmers, C., Sharma, N., Opavsky, R., Maiti, B., Wu, L., Wu, J., Orringer, D., Trikha, P., Saavedra, H. I., and Leone, G. (2007) E2f1, E2f2, and E2f3 Control E2F Target Expression and Cellular Proliferation via a p53-Dependent Negative Feedback Loop, 27, 65-78. 7. Wadsack, C., Tabano, S., Maier, A., Hiden, U., Alvino, G., Cozzi, V., Huttinger, M., Schneider, W. J., Lang, U., Cetin, I., and Desoye, G. (2007) Intrauterine growth restriction is associated with alterations in placental lipoprotein receptors and maternal lipoprotein composition, 292, E476-484. 8. Yesilaltay, A., Morales, M. G., Amigo, L., Zanlungo, S., Rigotti, A., Karackattu, S. L., Donahee, M. H., Kozarsky, K. F., and Krieger, M. (2006) Effects of Hepatic Expression of the High-Density Lipoprotein Receptor SR-BI on Lipoprotein Metabolism and Female Fertility, 147, 1577-1588. 9. Zhang, C., Yin, W., Liao, D., Huang, L., Tang, C., Tsutsumi, K., Wang, Z., Liu, Y., Li, Q., Hou, H., Cai, M., and Xiao, J. (2006) NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs, 47, 2055-2063. 10. Zhong, J., Gastaminza, P., Chung, J., Stamataki, Z., Isogawa, M., Cheng, G., McKeating, J. A., and Chisari, F. V. (2006) Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus and Host, 80, 11082-11093. 11. Akpovi, C.D., Yoon, S.R., Vitale, M.L. and Pelletier, R.M. (2006) The predominance of one of the SR-BI isoforms is associated with increased esterified cholesterol levels not apoptosis in mink testis, J. Lipid Res., 47, 2233-2247. 12. Azhar, S., Medicherla, S., Shen, W.-J., Fujioka, Y., Fong, L.G., Reaven, E. and Cooper, A.D. (2006) LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells, J. Lipid Res., 47, 2538-2550. 13. Sane, A.T., Sinnett, D., Delvin, E., Bendayan, M., Marcil, V., Menard, D., Beaulieu, J.-F. and Levy, E. (2006) Localization and role of NPC1L1 in cholesterol absorption in human intestine, J. Lipid Res., 47, 2112-2120. 14. Thomas-Moya, E., Gianotti, M., Proenza, A.M. and Llado, I. (2006) The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats, J. Lipid Res., 47, 2042-2048. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB400-104 Scavenger Receptor Class B Type I (SR-BI)'.
