NB300-717 TR beta / THRB / NR1A2 antibody
see related secondary antibodiessee all 18 TR beta / THRB / NR1A2 products
0.1 ml / US$ 465 no delivery possible
Quick Overview
Rabbit anti TR beta / THRB / NR1A2
Synonyms
Thyroid hormone receptor beta, ERBA2, THR1, THRB1, THRB2, , Nuclear receptor subfamily 1 group A member 2, erythroblastic leukemia viral (v-erb-a) oncogene homolog 2 avian, ERBABETA
Product review
Please read our product review about TR beta / THRB / NR1A2 : Antibody Panel to Thyroid Hormone Receptor (TR).
Product Description
Rabbit anti TR beta / THRB / NR1A2 , Presentation: Serum. Product is tested for Electrophoretic Mobility Shift Assay ( EMSA ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Electrophoretic Mobility Shift Assay ( EMSA ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Serum |
| Host | Rabbit |
| Catalog Number | NB300-717 |
| Swiss Prot. No. | P10828 |
| Quantity | 0.1 ml |
| Price | US$ 465 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Rabbit Polyclonal anti-Thyroid Hormone Receptor beta | |
| Alternate names | anti-c-erbA-2 antibody |
| Background | Thyroid hormone receptors (TR) are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences called hormone response elements following activation by the appropriate hormone. Thyroid hormones, through their interaction with TR, effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins. There are two forms of TR; TR alpha (on chromosome 17) and TR beta (on chromosome 3). Each of these isoforms also has two isoforms; TR alpha-1 and TRv alpha-2, and TR beta-1 and TR beta-2 respectively. TR alpha-1 and 2 are identical through amino acid 370 where their sequences diverge. TRv alpha-2, which does not bind T3 and is a strong negative regulator of the functional TR, is 80 amino acids longer than TR alpha-1. |
| Immunogen | Synthetic peptide: CIFHLDHDDVNDQSVSSAQTF, corresponding to amino acids 62-82 of Human Thyroid Hormone Receptor (beta). Swiss Num.: P10828 |
| Format | Purification: Whole antisera Purity: Whole antisera BufferSystem: Preservative: 0.05% Sodium Azide. Constituents: PBS |
| Applications | Western Blot, Gel Super Shift Assays, Immunocytochemistry, |
| Specificity | Species: Cross-reacts with Human and Rat. Not yet tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | Clin. Endocrinol., 53:469-477, 2000.
Endo., 131(5): 2419-2429, 1992. J. Clin. Endocrinol. Metab., Vol 87: 906-914, Feb 2002 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB300-717 TR beta / THRB / NR1A2 '.
