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NB300-634  KDEL antibody

see related secondary antibodies
see all 12 KDEL products
0.1 mg / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti KDEL

Synonyms

ER Marker,

Product Description

Rabbit anti KDEL , Presentation: Ig Fraction. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
ReactivityHamster ( Hst ), Rat ( Rt ), Mouse ( Ms )
PresentationIg Fraction
HostRabbit
Catalog NumberNB300-634
Quantity0.1 mg
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/p ...

Datasheet Extract

Rabbit Polyclonal anti-KDEL
Alternate namesanti-KDEL antibody, anti-Lys Asp Glu Leu antibody
BackgroundThe sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
ImmunogenSynthetic peptide: C T(643)GEEDTSEKDEL(654). Immunizing peptide corresponds to amino acid residues 643-654 from rat GRP 78.
Format
Purification: IgG purified
Purity: IgG purified
BufferSystem: 0.05% sodium azide.
Applicationsimmunofluorescence, immunoprecipitation, Western Blot
Specificity
Species: Cross-reacts with Hamster, Mouse and Rat.Does not cross-react with Human or African Green Monkey (COS cells).Not yet tested in other species.
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
ReferencesGeneral / background references:Orlandi PA Protein-disulfide isomerase-mediated reduction of the A subunit of cholera toxin in a human intestinal cell line. J Biol Chem 272:4591-9 (1997). Gething MJ & Sambrook J Protein folding in the cell. Nature 355:33-45 (1992). Takemoto H et al. Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase. Arch Biochem Biophys 296:129-36 (1992).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'NB300-634 KDEL'.