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NB300-1033  Death domain receptor 3 antibody

see related secondary antibodies
see all 45 Death domain receptor 3 products
0.05 mg / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti Death domain receptor 3

Synonyms

anti-Apo3 antibody, anti-Apoptosis inducing receptor AIR antibody, anti-Apoptosis mediating receptor DR3 antibody, anti-Apoptosis mediating receptor TRAMP antibody, anti-Death domain receptor 3 antibody, anti-Death Receptor 3 antibody, anti-Death receptor beta antibody, anti-LARD antibody, anti-Lymphocyte associated receptor of death antibody, anti-TNFRSF12 antibody, anti-TNFRSF25 antibody, anti-TR3 antibody, anti-Translocating chain association membrane protein antibody, anti-Tumor necrosis factor receptor superfamily member 25 antibody, anti-WSL1 protein antibody, anti-WSLLR antibody, Tumor necrosis factor receptor superfamily member 25

Product Description

Rabbit anti Death domain receptor 3 , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms )
PresentationPurified
HostRabbit
IsotypeIgG
Catalog NumberNB300-1033
Swiss Prot. No.Q93038
Quantity0.05 mg
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Polyclonal anti-DR3
Alternate namesanti-Apo3 antibody, anti-Apoptosis inducing receptor AIR antibody, anti-Apoptosis mediating receptor DR3 antibody, anti-Apoptosis mediating receptor TRAMP antibody, anti-Death domain receptor 3 antibody, anti-Death Receptor 3 antibody, anti-Death receptor beta antibody, anti-LARD antibody, anti-Lymphocyte associated receptor of death antibody, anti-TNFRSF12 antibody, anti-TNFRSF25 antibody, anti-TR3 antibody, anti-Translocating chain association membrane protein antibody, anti-Tumor necrosis factor receptor superfamily member 25 antibody, anti-WSL1 protein antibody, anti-WSLLR antibody
BackgroundApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD(1-5). The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.
ImmunogenSynthetic peptide, corresponding to amino acids 59-77 of Human DR3.
Swiss Num.: Q93038
Format
Purification: IgG purified
Purity: IgG purified
BufferSystem: PBS with 0.02% sodium azide
ApplicationsWB
Specificity
Species: Cross-reacts with Human, Rat and Mouse. Not yet tested in other species.
ReferencesGeneral / background references:Screaton GR et al. LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. Proc Natl Acad Sci U S A 94:4615-9 (1997). Bodmer JL et al. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). Immunity 6:79-88 (1997). Marsters SA et al. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B. Curr Biol 6:1669-76 (1996). Kitson J et al. A death-domain-containing receptor that mediates apoptosis. Nature 384:372-5 (1996). Chinnaiyan AM et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274:990-2 (1996).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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