NB200-179 15-PGHD (PGDH1) antibody
see related secondary antibodies
0.3 mg / US$ 435 no delivery possible
Quick Overview
Rabbit anti 15-PGHD (PGDH1)
Synonyms
15-Hydroxyprostaglandin dehydrogenase,
Product Description
Rabbit anti 15-PGHD (PGDH1) , Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | NB200-179 |
| Quantity | 0.3 mg |
| Price | US$ 435 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB200-179.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-15-PGDH | |
| Alternate names | anti-15-hydroxyprostaglandin dehydrogenase [NAD+] antibody; anti-Prostaglandin dehydrogenase 1 antibody; anti-HPGD antibody; anti-PGDH1 antibody |
| Concentration | 2.1 mg/ml |
| Background | 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is a novel tumor suppressor in the COX-2 pathway. The protein is found in many normal tissues and appears to be down-regulated in colorectal and lung carcinoma tissue. |
| Immunogen | Purified type I human placental 15-PGDH protein. |
| Format | Purification: protein A purified Purity: protein A purified BufferSystem: Tris-glycine, 150mM NaCl |
| Applications | immunofluorescence , Western Blot , Immunohistochemistry-Paraffin |
| Specificity | Species: This antibody reacts with human 15-PGDH protein. No other species have been tested. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| References | 1. Giannoulias, D., et al. Differentiatial changes in 15-Hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium. J. Clin. Endocrin. & Metabol. 87(3): 1345-1352, 2002. (Western blot, immunohistochemistry, immunofluorescence, human)
2. Ding, Y., et al. NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogen. 26(1): 65-72, 2005. 3. Yan, M., et al. 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-B-induced suppressor of human gastrointestinal cancers. PNAS. 101(50): 17468-17473, 2004. [Western blot, immunohistochemistry, human] 4. Tong, M. & Tai, H-H. Synergistic induction of NAD+-linked 15-Hydroxyprostaglandin dehydrogenase, by an androgen and IL-6 or forskolin in human prostate cancer cells. Endocrinology. 145(5): 2141-2147, 2004. [Western blot, human] 5. Backlund, M.G., et al. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. JBC. 280(5): 3217-3223, 2005. [Western blot, human] 6. Tai, C.L., et al. Monoclonal antibodies that inhibit the enzyme activity of NAD (+)-dependent 15-hydroxyprostaglandin dehydrogenase. J. Biochem. 267(1): 75-78, 1990. [Human] 7. Mann, J. R., et al. Repression of Prostaglandin Dehydrogenase by Epidermal Growth Factor and Snail Increases Prostaglandin E2 and Promotes Cancer Progression. Cancer Res. 66: 6649-6656, 2006. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB200-179 15-PGHD (PGDH1)'.
