NB200-174 p19 ARF antibody
see related secondary antibodiessee all 3 p19 ARF products
0.1 ml / US$ 435 no delivery possible
Quick Overview
Mouse anti p19 ARF 5-C3-1
Product Description
Mouse anti p19 ARF 5-C3-1, Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Mouse ( Ms ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG2b |
| Clone | 5-C3-1 |
| Catalog Number | NB200-174 |
| Quantity | 0.1 ml |
| Price | US$ 435 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB200-174.pdf |
Datasheet Extract
| Rat Monoclonal anti-p19ARF (5-C3-1) | |
| Alternate names | anti-ARF antibody, anti-CDK4 inhibitor P16 INK4 antibody, anti-CDK4I antibody, anti-CDKN2 antibody, anti-CDKN2A antibody, anti-Cell cycle negative regulator beta antibody, anti-CMM2 antibody, anti-Cyclin dependent kinase 4 inhibitor A antibody, anti-Cyclin dependent kinase inhibitor 2A antibody, anti-Cyclin dependent kinase inhibitor P12 antibody, anti-Cyclin dependent kinase inhibitor P16 antibody, anti-INK4 antibody, anti-INK4a ARF antibody, anti-Melanoma p16 inhibits CDK4 antibody, anti-MLM antibody, anti-MTS1 antibody, anti-Multiple tumor suppressor 1 antibody, anti-P14 antibody, anti-P16INK4a antibody, anti-P19 antibody, anti-TP16 antibody |
| Concentration | 1 mg/ml |
| Background | In humans, the multiple tumor suppressor 1 locus (MTS1) encodes two unrelated genes, p16INK4a and p19ARF. Although both act as cell proliferation inhibitors, their mechanisms of action are different. p19ARF works as part of a p53-dependent pathway to counter uncontrolled proliferation and oncogenic signals.
Mice lacking the p19ARF gene rapidly develop a broad spectrum of tumors. This result indicates that p19ARF is an important tumor suppressor. In addition, p19ARF helps prevent transforming signals from various onocoproteins via the p53 regulatory loop. These studies and others display the importance of p19ARF in cell cycle control and tumor suppression. |
| Immunogen | A synthetic peptide containing amino acids 54-75 of the murine p19ARF. |
| Format | Purification: protein A purified Purity: protein A purified BufferSystem: Tris-glycine, 150mM NaCl |
| Applications | immunohistochemistry , immunofluorescence , immunoprecipitation , Western Blot - 1 ug/ml (ECL)** |
| Specificity | Species: This antibody reacts with mouse protein. It does not react with human or Golden hamster. Armenian hamster has not been tested. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| References | 1. Bertwistle, D., et al. Hybridoma and Hybridomics. 23(6): 389-401 (2004)
2. Klochendler-Yeivin, A., Picarsky, E., and Yaniv, M. (2006) Increased DNA Damage Sensitivity and Apoptosis in Cells Lacking the Snf5/Ini1 Subunit of the SWI/SNF Chromatin Remodeling Complex, 26, 2661-2674. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB200-174 p19 ARF'.
