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NB120-3424  Rhodopsin antibody

see related secondary antibodies
see all 25 Rhodopsin products
0.1 mg / US$ 465 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti Rhodopsin

Synonyms

anti-OPN 2 antibody, anti-Opsin 2 antibody, anti-Retinitis Pigmentosa 4 antibody, anti-RHO antibody, anti-RP 4 antibody,

Product Description

Rabbit anti Rhodopsin , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
PresentationAff - Purified
HostRabbit
IsotypeIgG
Catalog NumberNB120-3424
Swiss Prot. No.P49912
Quantity0.1 mg
PriceUS$ 465 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Polyclonal anti-Rhodopsin
Alternate namesanti-OPN 2 antibody, anti-Opsin 2 antibody, anti-Retinitis Pigmentosa 4 antibody, anti-RHO antibody, anti-RP 4 antibody
BackgroundVision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light to an electrochemical signal begins when the membrane-bound protein rhodopsin absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentrations causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission. Rhodopsin activity is believed to be shut off by phosphorylation followed by binding of the soluble proteins arrestin.
ImmunogenSynthetic peptide: C-SKTETSQVAPA, corresponding to amino acids 338-348 of Cow Rhodopsin.
Swiss Num.: P49912
Format
Purification: Immunogen affinity purified
Purity: Immunogen affinity purified
BufferSystem: PBS, 1 mg/ml BSA and 0.05% sodium azide
ApplicationsWB
Specificity
Species: Cross-reacts with Cow. Does not cross-react with Sheep. Not yet tested in other species.
ReferencesGeneral / background references:Ishizawa Y et al. G protein-coupled receptors as direct targets of inhaled anesthetics. Mol Pharmacol 61:945-52 (2002). Arshavsky VY Rhodopsin phosphorylation: from terminating single photon responses to photoreceptor dark adaptation. Trends Neurosci 25:124-6 (2002).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'NB120-3424 Rhodopsin'.