NB110-85473 CD62E / SELE / E-selectin antibody
see related secondary antibodiessee all 35 CD62E / SELE / E-selectin products
0.1 mg / US$ 515 no delivery possible
Quick Overview
Rat anti CD62E / SELE / E-selectin RM0034-9J12
Synonyms
ELAM-1, LECAM2, SELE, ELAM1, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, CD62 antigen-like family member E
Product Description
Rat anti CD62E / SELE / E-selectin RM0034-9J12, Presentation: Purified. Product is tested for Flow cytometry ( F ), Paraffin Sections ( P )
Properties
| Applications | Flow cytometry ( F ), Paraffin Sections ( P ) |
| Reactivity | Mouse ( Ms ) |
| Presentation | Purified |
| Host | Rat |
| Isotype | IgG2 |
| Clone | RM0034-9J12 |
| Catalog Number | NB110-85473 |
| Swiss Prot. No. | Q00690 |
| Quantity | 0.1 mg |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rat Monoclonal anti-E-Selectin (RM0034-9J12) | |
| Alternate names | anti-CD 62E antibody, anti-CD62E antigen antibody, anti-E selectin antibody, anti-ELAM 1 antibody, anti-ELAM antibody, anti-ELAM1 antibody, anti-Endothelial adhesion molecule 1 antibody, anti-Endothelial leukocyte adhesion molecule 1 antibody, anti-ESEL antibody, anti-LECAM 2 antibody, anti-LECAM2 antibody, anti-Leukocyte endothelial cell adhesion molecule 2 antibody, anti-SELE antibody, anti-Selectin E antibody, anti-SelectinE antibody |
| Background | CD62E is also known as endothelial leukocyte adhesion molecule 1 (ELAM1) or E selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). Selectins are C type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. CD62E (E selectin) is an endothelial cell specific selectin that is expressed on cytokine induced endothelial cells only after activation with proinflammatory cytokines. In vitro experiments have shown that IL1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of CD62E in an NFkB dependent signalling cascade. CD62E has been associated with blood vessel endothelium in diverse inflammatory situations. The main ligands recognised by CD62E are oligosaccharides related to sialyl lewis x. |
| Immunogen | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with cytokine stimulated-mouse endothelial membrane protein. Swiss Num.: Q00690 |
| Format | Purification: protein G purified Purity: protein G purified BufferSystem: PBS |
| Applications | flow cytometry / FACS analysis 1:100-1:1000, Immunohistochemistry-Paraffin 1:100-1:400, |
| Specificity | Species: This antibody is reactive against Mouse. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1371B | Rat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1371F | Rat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1371T | Rat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1371TR | Rat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1371HRP | Rat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1371AP | Rat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 335 | |||||
| R1439C2 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1439C3 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1439C35 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1439C5 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1439C55 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1413R | Rat IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Ms, Rb, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1428R | Rat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
| R1415R | Rat IgG F(ab')2 F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-85473 CD62E / SELE / E-selectin'.
