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NB110-74734  ACCN4 antibody

see related secondary antibodies
0.1 ml / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti ACCN4

Synonyms

anti-Amiloride-sensitive cation channel 4 pituitary antibody, anti-acid-sensing ion channel 4 antibody, anti-spinal chord ASIC antibody, anti-Spasic antibody, anti-BNAC4 antibody, anti-MGC17248 antibody, anti-MGC24860 antibody,

Product Description

Rabbit anti ACCN4 , Presentation: Serum. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFrozen sections ( C ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Mouse ( Ms ), Rat ( Rt )
PresentationSerum
HostRabbit
Catalog NumberNB110-74734
Quantity0.1 ml
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Polyclonal anti-ACCN4
Alternate namesanti-Amiloride-sensitive cation channel 4 pituitary antibody, anti-acid-sensing ion channel 4 antibody, anti-spinal chord ASIC antibody, anti-Spasic antibody, anti-BNAC4 antibody, anti-MGC17248 antibody, anti-MGC24860 antibody
BackgroundFUNCTION: Probable cation channel with high affinity for sodium. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception.; SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins (Probable).; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.; TISSUE SPECIFICITY: This gene is predominantly expressed in the pituitary gland. Expressed in brain, spinal chord and dorsal root ganglion (DRG). Expressed by a subset of sensory neurons in the DRG. Expressed by granule cells in the cerebellar cortex. In hippocampus, expression is detected in dentate gyrus granule cells, in pyramidal cells of CA1-CA3 subfields and in interneurons of the striatum oriens and radiatum of all subfields. In cerebral cortex expressed in small, medium and large pyramidal cells in layers 2, 3 and 5 respectively. Also expressed in striatum, globus pallidus, inferior and superior calliculi, amygdala, magnocellular preoptic nucleus, islands of Calleja and large neurons of olfactory tubercules.; DEVELOPMENTAL STAGE: Highly expressed in newborn spinal chord but hardly detected in the cerebellum compared to adult. Expressed at postnatal day 1 in ependymal cells lining the central canal of spinal chord and in motor neurons. In adult, expression decreases in ependymal cells and increases in motor neurons. The number of positive interneurons decreases but the individual interneuron expression increases in adult spinal chord compared to newborn.; MISCELLANEOUS: In vitro, has no proton-gated channel activity.
ImmunogenA synthetic peptide as a part of human, rat & mouse amiloride-sensitive cation channel 4 (ACCN4, ASIC4) conjugated to immunogenic carrier protein was used as the immunogen.
Format
Purification: Whole antisera
Purity: Whole antisera
BufferSystem: Lyophilised in PBS
Applicationsimmunohistochemistry, Western Blot 1:300
Specificity
Species: Human, rat and mouse. Other species not yet tested.
StorageReconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1)
References1. Gruender S, et al. NeuroReport 11:1607-1611(2000).
2. Akopian A.N, et al. NeuroReport 11:2217-2222(2000).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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