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NB110-74716  ocular albinism type 1 protein antibody

see related secondary antibodies
see all 4 ocular albinism type 1 protein products
0.1 ml / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti ocular albinism type 1 protein

Synonyms

anti-ALBINISM OCULAR TYPE I antibody, anti-G protein coupled receptor 143 antibody, anti-GPR143 antibody, anti-MOA1 antibody, anti-NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody, anti-OA1 antibody, anti-Ocular albinism type 1 protein antibody, anti-Ocular albinism type 1 protein homolog antibody, anti-Ocular albinism1 Nettleship Falls type antibody, anti-Ocular albinism1 Nettleship-Falls type antibody,

Product Description

Rabbit anti ocular albinism type 1 protein , Presentation: Serum. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFrozen sections ( C ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationSerum
HostRabbit
Catalog NumberNB110-74716
Quantity0.1 ml
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Polyclonal anti-ocular albinism type 1 protein
Alternate namesanti-ALBINISM OCULAR TYPE I antibody, anti-G protein coupled receptor 143 antibody, anti-GPR143 antibody, anti-MOA1 antibody, anti-NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody, anti-OA1 antibody, anti-Ocular albinism type 1 protein antibody, anti-Ocular albinism type 1 protein homolog antibody, anti-Ocular albinism1 Nettleship Falls type antibody, anti-Ocular albinism1 Nettleship-Falls type antibody
BackgroundOcular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes.

FUNCTION: Not known; binds heterotrimeric G proteins.
SUBCELLULAR LOCATION: Melanosome membrane; Multi-pass membrane protein. Note: Targeted to intracellular organelles, namely the melanosomes in pigment cells.
TISSUE SPECIFICITY: Exclusively expressed in pigment cells.
DISEASE: Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.
ImmunogenA synthetic peptide as a part of human ocular albinism type 1 protein (G protein-coupled receptor 143 or GPR143, OA1) conjugated to immunogenic carrier protein was used as the immunogen.
Format
Purification: Whole antisera
Purity: Whole antisera
BufferSystem: Lyophilised in PBS
Applicationsimmunohistochemistry, Western Blot 1:300
Specificity
Species: Human. Other species not yet tested.
StorageReconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1)
References1. Bassi M.T, et al. Nat. Genet. 10:13-19(1995).
2. Oetting W.S, et al. Hum. Mutat. 13:99-115(1999).
3. Basrur V, et al. J. Proteome Res. 2:69-79(2003).
4. Chi A, et al. J. Proteome Res. 5:3135-3144(2006).
5. Schiaffino M.V, et al. Hum. Mol. Genet. 4:2319-2325(1995).
6. Schnur R.E, et al. Am. J. Hum. Genet. 62:800-809(1998).
7. Schiaffino M.V, et al. Nat. Genet. 23:108-112(1999).
8. Bassi M.T, et al. Hum. Genet. 108:51-54(2001).

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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