NB110-60998 CD62E / SELE / E-selectin antibody
see related secondary antibodiessee all 35 CD62E / SELE / E-selectin products
0.1 mg / US$ 525 no delivery possible
Quick Overview
Mouse anti CD62E / SELE / E-selectin MM0032-9E7
Synonyms
ELAM-1, LECAM2, SELE, ELAM1, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, CD62 antigen-like family member E
Product Description
Mouse anti CD62E / SELE / E-selectin MM0032-9E7, Presentation: Purified. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG2 |
| Clone | MM0032-9E7 |
| Catalog Number | NB110-60998 |
| Swiss Prot. No. | P16581 |
| Quantity | 0.1 mg |
| Price | US$ 525 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Mouse Monoclonal anti-E Selectin (MM0032-9E7) | |
| Alternate names | Anti-CD 62E antibody; Anti-CD62E antigen antibody; Anti-E-selectin antibody; Anti-Eselectin antibody
Anti-ELAM 1 antibody; Anti-ELAM antibody; Anti-ELAM1 antibody; Anti-Endothelial adhesion molecule 1 antibody; Anti-Endothelial leukocyte adhesion molecule 1 antibody; Anti-ESEL antibody; Anti-LECAM 2 antibody; Anti-LECAM2 antibody; Anti-Leukocyte endothelial cell adhesion molecule 2 antibody; Anti-SELE antibody; Anti-Selectin E antibody; Anti-Selectin-E antibody; Anti-SelectinE antibody |
| Background | CD62E is also known as endothelial leukocyte adhesion molecule 1 (ELAM1) or E selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). Selectins are C type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. CD62E (E selectin) is an endothelial cell specific selectin that is expressed on cytokine induced endothelial cells only after activation with proinflammatory cytokines. In vitro experiments have shown that IL1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of CD62E in an NFkB dependent signalling cascade. CD62E has been associated with blood vessel endothelium in diverse inflammatory situations. The main ligands recognised by CD62E are oligosaccharides related to sialyl lewis xx. This antibody inhibits neutrophil adhesion to E-selectin and to P-selectin. E-selectin (ELAM-1) is expressed on the surface of activated endothelial cells.
|
| Immunogen | This antibody was produced from a hybridoma (mouse myeloma fused with
spleen cells from a mouse immunized with purified human recombinant E-selectin protein. Swiss Num.: P16581 |
| Format | Purification: protein G purified Purity: protein G purified BufferSystem: PBS |
| Applications | immunohistochemistry 1:50-1:200, Western Blot 1:500-1:2000, |
| Specificity | Species: This antibody is reactive against human. Not yet tested in other species. |
| Storage | Reconstitute in 0.5 ml PBS. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-60998 CD62E / SELE / E-selectin'.
