NB110-57301 p53 antibody
see related secondary antibodiessee all 282 p53 products
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti p53 E26
Synonyms
Phosphoprotein p53, TP53, NY-CO-13, TRP53, , Cellular tumor antigen p53, Tumor suppressor p53
Product review
Please read our product review about p53: Antibodies to p53 and p53 interacting proteins.
Product Description
Rabbit anti p53 E26, Presentation: Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | E26 |
| Catalog Number | NB110-57301 |
| Swiss Prot. No. | P04637 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-p53 (E26) | |
| Alternate names | Antigen NY-CO-13 antibody
Cellular tumor antigen p53 antibody Cys 51 Stop antibody HGNC11998 antibody LFS1 antibody p53 Cellular Tumor Antigen antibody p53 Tumor Suppressor antibody Phosphoprotein p53 antibody TP53 antibody Transformation related protein 53 antibody TRP53 antibody Tumour Protein p53 antibody |
| Background | p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair (1,2). The gene for the nuclear phosphoprotein p53 is the most commonly mutated gene yet identified in human cancers (3). p53 is frequently mutated or inactivated in about 60% of cancers (4,5). |
| Immunogen | Swiss Num.: P04637 |
| Format | BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.05% BSA. |
| Applications | immunohistochemistry, Western Blot, Immunocytochemistry |
| Specificity | Species: Reacts in human and rat. Does not react in mouse. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell 88: 323?331 (1997).
2. Lakin, N.D. and S.P. Jackson. Regulation of p53 in response to DNA damage. Oncogene 18: 7644?7655 (1999). 3. Vogelstein, B. Cancer. A deadly inheritance. Nature 348: 681?2(1990). 4. Hoolstein, M., et al. p53 mutations in human cancers. Science 253: 49?53(1991). 5. Harris C.C. p53: at the crossroads of molecular carcinogenesis and risk assessment. Science 262: 1980?1981(1993). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-57301 p53'.
