NB110-57291 p190-B RhoGAP antibody
see related secondary antibodies
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti p190-B RhoGAP EP489Y
Synonyms
ARF antibody CCM2 antibody CDK4 Inhibitor antibody CDK4I antibody CDKN2 antibody CDKN2A antibody CMM2 antibody Cyclin dependent kinase 4 inhibitor A antibody Cyclin Dependent Kinase Inhibitor 2A antibody Cyclin dependent kinase inhibitor 2A isoforms 1/2/3,
Product Description
Rabbit anti p190-B RhoGAP EP489Y, Presentation: Aff - Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | EP489Y |
| Catalog Number | NB110-57291 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-p190-B RhoGAP (EP489Y) | |
| Alternate names | anti-ARF antibody, anti-CCM2 antibody, anti-CDK4 Inhibitor antibody, anti-CDK4I antibody, anti-CDKN2 antibody, anti-CDKN2A antibody, anti-CMM2 antibody, anti-Cyclin dependent kinase 4 inhibitor A antibody, anti-Cyclin Dependent Kinase Inhibitor 2A antibody, anti-Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody, anti-INK4 antibody, anti-INK4A antibody, anti-MLM antibody, anti-MTS1 antibody, anti-Multiple Tumor Supressor 1 antibody, anti-p14 antibody, anti-p14(ARF) antibody, anti-p14ARF antibody, anti-p16 antibody, anti-p16 INK4 antibody, anti-p16INK4 antibody, anti-p16INK4a antibody, anti-p19 antibody, anti-p19(ARF) antibody, anti-TP16 antibody |
| Background | The p190 Rho GTPase activating protein RhoGAP) family includes two closely related proteins, p190-A and p190-B. p190-B contains an N-terminal GTPase domain and a C-terminal Rho-GAP domain (1). p190-B can be directly phosphorylated on a single identified tyrosine residue by the activated insulin and IGF-1 receptors. This phosphorylation causes p190-B to translocate to the lipid rafts of the plasma membrane, where it can facilitate the inactivation of the Rho GTPase. P190-B also has been shown to be tyrosine phosphorylated by c-Src and v-Src. Additionall; the GAP domain of p190-B as shown to attenuate signal-transducing activity of Rac, Rho and CDC42 (2-3). |
| Immunogen | Recombinant full length protein (Human) of p16/INK4a |
| Format | Purification: Ascites Purity: Ascites BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.5% BSA. |
| Applications | flow cytometry / FACS analysis , immunohistochemistry , immunoprecipitation , Western Blot |
| Specificity | Species: Reacts in human, mouse, and rat. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Burbelo et al. J. Biol. Chem. 270: 30919-30926, 1995.
2. Peter et al. Volume 270, Number 52, Issue of December 29, 1995 pp. 30919-30926 3. DZ Wang, MS Nur-E-Kamal, A Tikoo, W Montague and H Maruta. Cancer Research, Vol 57, Issue 12 2478-2484. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-57291 p190-B RhoGAP'.
