NB110-56930 Death domain-associated protein 6 antibody
see related secondary antibodiessee all 23 Death domain-associated protein 6 products
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti Death domain-associated protein 6 E94
Synonyms
DAXX, BING2, DAP6, hDaxx, , ETS1-associated protein 1, EAP1, Fas death domain-associated protein
Product Description
Rabbit anti Death domain-associated protein 6 E94, Presentation: Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | E94 |
| Catalog Number | NB110-56930 |
| Swiss Prot. No. | O35613 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-DAXX (E94) | |
| Alternate names | antibody, anti-BING 2 antibody, anti-BING2 antibody, anti-DAP 6 antibody, anti-DAP6 antibody, anti-Death associated protein 6 antibody, anti-Death domain associated protein 6 antibody, anti-EAP 1 antibody, anti-EAP1 antibody, anti-ETS1 associated protein 1 antibody, anti-Fas death domain associated protein antibody, anti-hDaxx antibody, anti-MGC126245 antibody, anti-MGC126246 antibody |
| Background | Daxx is a nuclear protein that has been found to the enhance Fas-mediated apoptosis and activate the JNK pathway (1). Apoptosis signal-regulating kinase 1 (ASK1) controls the dual function of Daxx as a transcriptional repressor in the nucleus and as a proapoptotic signal mediator in the cytoplasm (2). Daxx associates with various proteins, including promyelocytic leukemia protein (PML) and heat shock protein 27, lending significance to their roles i |
| Immunogen | Swiss Num.: O35613 |
| Format | BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Applications | flow cytometry / FACS analysis, immunohistochemistry, Western Blot, Immunocytochemistry |
| Specificity | Species: reacts in Human. Does not react in Mouse or Rat. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Yang, X., et al. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89: 1067?1076 (1997). 2. Ko, Y.G., et al. Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm. J. Biol. Chem. 276: 39103?6 (2001). 3. Zhong, S., et al. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. J. Exp. Med. 191: 631?40 (2000). 4. Charette, S.J., et al. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Mol. Cell Biol. 20: 7602?12 (2000). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-56930 Death domain-associated protein 6'.
