NB100-79888 ACAT1 / SOAT1 antibody
see related secondary antibodiessee all 4 ACAT1 / SOAT1 products
0.1 ml / US$ 485 no delivery possible
Quick Overview
Rabbit anti ACAT1 / SOAT1
Synonyms
Anti-Acyl coenzyme A:cholesterol acyltransferase antibody, Anti-ACAT antibody, Anti-Monocyte/macrophage serine esterase antibody, Anti-HMSE antibody, Anti-Serine esterase 1 antibody, Anti-Brain carboxylesterase hBr1 antibody, Anti-Triacylglycerol hydrolase antibody, Anti-TGH antibody, Anti-Egasyn antibody, Anti-Retinyl ester hydrolase antibody, Anti-REH antibody, Acyl coenzyme A:cholesterol acyltransferase 1
Product Description
Rabbit anti ACAT1 / SOAT1 , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB ), Frozen sections ( C ), Immunofluorescence ( IF )
Properties
| Applications | Western blot / Immunoblot ( WB ), Frozen sections ( C ), Immunofluorescence ( IF ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-79888 |
| Swiss Prot. No. | P35610 |
| Quantity | 0.1 ml |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-ACAT | |
| Alternate names | Anti-Acyl coenzyme A:cholesterol acyltransferase antibody, Anti-ACAT antibody, Anti-Monocyte/macrophage serine esterase antibody, Anti-HMSE antibody, Anti-Serine esterase 1 antibody, Anti-Brain carboxylesterase hBr1 antibody, Anti-Triacylglycerol hydrolase antibody, Anti-TGH antibody, Anti-Egasyn antibody, Anti-Retinyl ester hydrolase antibody, Anti-REH antibody |
| Background | Acely-CoA:cholestorl acyltransferase (ACAT) is an integral membrane enzyme that belongs to type-B carboxylesterase/lipase family. ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A (1). ACAT also function as a regulator of intracellular cholesterol homeostasis at single cell level. Two isoform of ACAT exists, ACAT1 and ACAT2, are expressed in liver and intestine. However, ACAT1 is only found in macrophages and SMCs (2). The accumulation of cholesteryl esters produced by ACAT in macrophages can lead to foam cell formation, an indication of early stage atherosclerosis. ACAT activity has been linked to Alzehimer?s Diease, condition caused by excess amount of amyloid beta-peptide (Abeta). Atherogenic lipoproteins activate ACAT activity, where active ACAT can modulate the level of Abeta (3). |
| Immunogen | A synthetic peptide corresponding to residues in human ACAT was used as immunogen. Swiss Num.: P35610 |
| Format | Purification: Affinity purified Purity: Affinity purified |
| Applications | Western Blot 1:500,immunohistochemistry 1:100-1:250,Immunocytochemistry 1:100-1:250 |
| Specificity | Species: This antibody is reactive against Human, Mouse, Rat |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Buhman KF et al. Biochim Biophys Acta 1529(1-3):142-54, 2000 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-79888 ACAT1 / SOAT1'.
