NB100-75351 G protein beta subunit-like / GBL antibody
see related secondary antibodiessee all 12 G protein beta subunit-like / GBL products
0.05 mg / US$ 485 no delivery possible
Quick Overview
Chicken anti G protein beta subunit-like / GBL
Synonyms
LST8, GBL, TORC subunit LST8, mLST8, G protein beta subunit-like, Protein GbetaL, Gable, Target of rapamycin complex subunit LST8
Product Description
Chicken anti G protein beta subunit-like / GBL , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Chicken |
| Catalog Number | NB100-75351 |
| Swiss Prot. No. | Q9BVC4 |
| Quantity | 0.05 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Chicken Polyclonal anti-G protein beta subunit-like | |
| Alternate names | anti-G protein beta subunit like antibody, anti-GBL antibody, anti-GBL protein antibody, anti-MGC111011 antibody |
| Background | GßL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors. It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with GßL and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis. The binding of GßL to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth. |
| Immunogen | The immunogen for this antibody was a sequence from 20a.a. to 270a.a. from G protein beta subunit-like(a 326a.a. long protein) Swiss Num.: Q9BVC4 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Phosphate-Buffered Saline. |
| Applications | Western Blot |
| Specificity | Species: This antibody is reactive against Human, mouse, rat. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| References | [1] Rodgers,B.D., Levine,M.A., Bernier,M. and Montrose-Rafizadeh,C., et al. Insulin regulation of a novel WD-40 repeat protein in adipocytes
[2] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
11 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1300B | Chicken IgG (H&L) | ||||||
| Rabbit | Biotin | 1.5 mg / US$ 325 | |||||
| R1300F | Chicken IgG (H&L) | ||||||
| Rabbit | FITC | 1.5 mg / US$ 295 | |||||
| R1300T | Chicken IgG (H&L) | ||||||
| Rabbit | TRITC | 1.5 mg / US$ 305 | |||||
| R1300TR | Chicken IgG (H&L) | ||||||
| Rabbit | Texas Red | 1.5 mg / US$ 335 | |||||
| R1300HRP | Chicken IgG (H&L) | ||||||
| Rabbit | HRP | 1.5 mg / US$ 315 | |||||
| R1300AP | Chicken IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 355 | |||||
| R1434C2 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1434C3 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1434C35 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1434C5 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1434C55 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
Click here to see all secondary antibodies for 'NB100-75351 G protein beta subunit-like / GBL'.
