NB100-75323 CD305 / LAIR-1a antibody
see related secondary antibodies
0.05 mg / US$ 485 no delivery possible
Quick Overview
Chicken anti CD305 / LAIR-1a
Synonyms
hLAIR1, LAIR1, , , Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin-like receptor 1, NK Cell Marker
Product review
Please read our product review about CD305 / LAIR-1a: NK-Cell Markers.
Product Description
Chicken anti CD305 / LAIR-1a , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Chicken |
| Catalog Number | NB100-75323 |
| Swiss Prot. No. | Q6GTX8 |
| Quantity | 0.05 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Chicken Polyclonal anti-LAIR1 isoform a | |
| Alternate names | anti-5133400O11Rik antibody, anti-CD305 antibody, anti-D7Bwg0421e antibody, anti-LAIR 1 antibody, anti-LAIR1 protein antibody, anti-Leukocyte associated Ig like receptor 1 antibody, anti-Leukocyte associated immunoglobulin like receptor 1 antibody |
| Background | LAIR1 is a transmembrane glycoprotein(~32kDa) expressed on the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR1 recruits SHP1 and SHP2 tyrosine phosphatases upon activation, and cross-linking of the LAIR1 molecule on NK cells results in strong inhibition of NK cell mediated cytotoxicity. |
| Immunogen | The immunogen for this antibody was a sequence from 25a.a. to 122a.a. from LAIR1 isoform a(a 287a.a. long protein) Swiss Num.: Q6GTX8 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Phosphate-Buffered Saline. |
| Applications | Western Blot |
| Specificity | Species: This antibody is reactive against Human. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| References | [1] Meyaard,L., et al. Leukocyte associated Ig-like receptor (LAIR)
[2] Aoukaty,A., Lee,I.F., Wu,J. and Tan,R., et al. Chronic active Epstein-Barr virus infection associated with low expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on natural killer cells [3] Saverino,D., Fabbi,M., Merlo,A., Ravera,G., Grossi,C.E. and Ciccone,E. Surface density expression of the leukocyte-associated Ig-like receptor-1 is directly related to inhibition of human T-cell functions [4] Meyaard,L., van der Vuurst de Vries,A.R., de Ruiter,T., Lanier,L.L., Phillips,J.H. and Clevers,H. The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR) [5] Sathish,J.G., Johnson,K.G., Fuller,K.J., LeRoy,F.G., Meyaard,L., Sims,M.J. and Matthews,R.J. Constitutive association of SHP-1 with leukocyte-associated Ig-like receptor-1 in human T cells [6] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. [7] , Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |
11 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1300B | Chicken IgG (H&L) | ||||||
| Rabbit | Biotin | 1.5 mg / US$ 325 | |||||
| R1300F | Chicken IgG (H&L) | ||||||
| Rabbit | FITC | 1.5 mg / US$ 295 | |||||
| R1300T | Chicken IgG (H&L) | ||||||
| Rabbit | TRITC | 1.5 mg / US$ 305 | |||||
| R1300TR | Chicken IgG (H&L) | ||||||
| Rabbit | Texas Red | 1.5 mg / US$ 335 | |||||
| R1300HRP | Chicken IgG (H&L) | ||||||
| Rabbit | HRP | 1.5 mg / US$ 315 | |||||
| R1300AP | Chicken IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 355 | |||||
| R1434C2 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1434C3 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1434C35 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1434C5 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1434C55 | Chicken IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
Click here to see all secondary antibodies for 'NB100-75323 CD305 / LAIR-1a'.
