NB100-74624 CIZ1 antibody
see related secondary antibodiessee all 2 CIZ1 products
0.1 mg / US$ 515 no delivery possible
Quick Overview
Rabbit anti CIZ1
Synonyms
anti-CIZ1 antibody, anti-CIZ-1 antibody, anti-CDKN1A interacting zinc finger protein 1 antibody, anti-ZNF356 antibody, anti-zinc finger protein 356 antibody, anti-NP94 antibody, anti-nuclear protein NP94 antibody, anti- LSFR1 antibody,
Product Description
Rabbit anti CIZ1 , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB ), Immunoprecipitation ( IP )
Properties
| Applications | Western blot / Immunoblot ( WB ), Immunoprecipitation ( IP ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-74624 |
| Quantity | 0.1 mg |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-CIZ1 | |
| Alternate names | anti-CIZ1 antibody, anti-CIZ-1 antibody, anti-CDKN1A interacting zinc finger protein 1 antibody, anti-ZNF356 antibody, anti-zinc finger protein 356 antibody, anti-NP94 antibody, anti-nuclear protein NP94 antibody, anti- LSFR1 antibody |
| Concentration | 1 mg/ml |
| Background | CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication. |
| Immunogen | The epitope recognized by this antibody maps to a region between residue 848 and 898 of human CDKN1A interacting zinc finger protein 1 using the numbering given in entry NP_036259.2 (GeneID 25792). |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Tris-citrate/phosphate buffer, pH 7 to 8 |
| Applications | Western Blot 1:2000-1:10000, immunoprecipitation 2-5 ug/mg lysate |
| Specificity | Species: Human. |
| Storage | Store at 4C. Do not freeze. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-74624 CIZ1'.
