NB100-66129 Death domain-associated protein 6 antibody
see related secondary antibodiessee all 23 Death domain-associated protein 6 products
0.1 mg / US$ 465 no delivery possible
Quick Overview
Rabbit anti Death domain-associated protein 6
Synonyms
anti-BING 2 antibody, anti-BING2 antibody, anti-DAP 6 antibody, anti-DAP6 antibody, anti-Death associated protein 6 antibody, anti-Death domain associated protein 6 antibody, anti-EAP 1 antibody, anti-EAP1 antibody, anti-ETS1 associated protein 1 antibody, anti-Fas death domain associated protein antibody, anti-hDaxx antibody, anti-MGC126245 antibody, anti-MGC126246 antibody, Fas death domain-associated protein
Product Description
Rabbit anti Death domain-associated protein 6 . Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Monkey ( Mky ) |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-66129 |
| Swiss Prot. No. | O35613 |
| Quantity | 0.1 mg |
| Price | US$ 465 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-DAXX | |
| Alternate names | anti-BING 2 antibody, anti-BING2 antibody, anti-DAP 6 antibody, anti-DAP6 antibody, anti-Death associated protein 6 antibody, anti-Death domain associated protein 6 antibody, anti-EAP 1 antibody, anti-EAP1 antibody, anti-ETS1 associated protein 1 antibody, anti-Fas death domain associated protein antibody, anti-hDaxx antibody, anti-MGC126245 antibody, anti-MGC126246 antibody |
| Concentration | 0.5 mg/ml |
| Background | Apoptosis, or programmed cell death, occurs duringnormal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways. |
| Immunogen | Peptide corresponding to amino acids 722-740 at the C-terminus of human DAXX Swiss Num.: O35613 |
| Format | BufferSystem: Phosphate buffered saline |
| Applications | Western Blot |
| Specificity | Species: Reacts with: Primate, Human, Mouse |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| References | 1. Yang, X. et al. (1997) Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89: 1067-1076.
2. Kiriakidou, M. et al. (1997) Cloning and expression of primate Daxx cDNAs and mapping of the human gene to chromosome 6p21.3 in the MHC region. DNA Cell Biol. 16: 1289-1298. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-66129 Death domain-associated protein 6'.
