NB100-66118 Apolipoprotein J (Clusterin) antibody
see related secondary antibodiessee all 20 Apolipoprotein J products
0.1 mg / US$ 485 no delivery possible
Quick Overview
Rabbit anti Apolipoprotein J (Clusterin)
Synonyms
anti-Apolipoprotein J antibody, anti-AAG 4 antibody, anti-AAG4 antibody, anti-Aging associated protein 4 antibody, anti-APO J antibody, anti-APOJ antibody, anti-Apolipoprotein J antibody, anti-ApolipoproteinJ antibody, anti-CLI antibody, anti-CLU antibody, anti-Clusterin alpha chain antibody, anti-clusterin antibody, anti-Clusterin beta chain antibody, anti-Clusterin precursor antibody, anti-Complement associated protein SP 40 40 antibody, anti-Complement associated protein SP 40 antibody, anti-Complement associated protein SP40 antibody, anti-Complement cytolysis inhibitor antibody, anti-Complement lysis inhibitor antibody, anti-KUB 1 antibody, anti-KUB1 antibody, anti-MGC24903 antibody, anti-NA1/NA2 antibody, anti-SGP 2 antibody, anti-SGP2 antibody, anti-SP 40 antibody, anti-SP40 antibody, anti-Sufated glycoprotein 2 antibody, anti-Sulfated glycoprotein 2 antibody, anti-Testosterone repressed prostate message 2 antibody, anti-TRPM 2 antibody, anti-TRPM2 antibody,
Product Description
Rabbit anti Apolipoprotein J (Clusterin) , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NB100-66118 |
| Swiss Prot. No. | P10909 |
| Quantity | 0.1 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-CLUSTERIN | |
| Alternate names | anti-Apolipoprotein J antibody, anti-AAG 4 antibody, anti-AAG4 antibody, anti-Aging associated protein 4 antibody, anti-APO J antibody, anti-APOJ antibody, anti-Apolipoprotein J antibody, anti-ApolipoproteinJ antibody, anti-CLI antibody, anti-CLU antibody, anti-Clusterin alpha chain antibody, anti-clusterin antibody, anti-Clusterin beta chain antibody, anti-Clusterin precursor antibody, anti-Complement associated protein SP 40 40 antibody, anti-Complement associated protein SP 40 antibody, anti-Complement associated protein SP40 antibody, anti-Complement cytolysis inhibitor antibody, anti-Complement lysis inhibitor antibody, anti-KUB 1 antibody, anti-KUB1 antibody, anti-MGC24903 antibody, anti-NA1/NA2 antibody, anti-SGP 2 antibody, anti-SGP2 antibody, anti-SP 40 antibody, anti-SP40 antibody, anti-Sufated glycoprotein 2 antibody, anti-Sulfated glycoprotein 2 antibody, anti-Testosterone repressed prostate message 2 antibody, anti-TRPM 2 antibody, anti-TRPM2 antibody |
| Concentration | 1.0mg/ml |
| Background | At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individual's relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL).
Apolipoprotein J is the major secreted product of Sertoli cells and is thought to play a critical role in spermatogenesis. The protein was shown to be a normal constituent of human blood and is also thought to be a control mechanism of the complement cascade. It prevents the binding of a C5b-C7 complex to the membrane of the target cell and in this way inhibits complement-mediated cytolysis. Apolipoprotein J is overexpressed in human prostate and breast cancers and in squamous cell carcinomas. Suppression of Apolipoprotein J renders these cells sensitive to chemotherapeutic drug-mediated apoptosis. It has been proposed that elevated levels of Apolipoprotein J may promote oncogenic transformation and tumor progression by interfering with BAX proapoptotic activities. |
| Immunogen | Recombinant human clusterin isoform 1.
Swiss Num.: P10909 |
| Format | Purification: Affinity purified Purity: Affinity purified BufferSystem: Phosphate buffered saline |
| Applications | Western Blot 0.5 - 1.0ug/ml |
| Specificity | Species: Human. Not yet tested in other species. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| References | 1. Trougakos, I. and Gonos, E. (2002) Clusterin/Apolipoprotein J in human aging and cancer. Int. J. Biochem. Cell Biol. 34: 1430-1448.
2. Calero, M. et al. (2005) Clusterin and Alzheimer?s disease. Subcell. Biochem. 38: 273-298. 3. Leskov, K. et al. (2003) Synthesis and Functional Analyses of Nuclear Clusterin, a Cell Death Protein. J. Biol.Chem. 278: 11590-11600. 4. Carreras, I. et al. (2005) Upregulation of clusterin/apolipoprotein J in lactacystin-treated SH-SY5Y cells. J. Neurosci. Res. 79: 495-502. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-66118 Apolipoprotein J (Clusterin) '.
