NB100-40911 CDKN2A antibody
see related secondary antibodiessee all 6 CDKN2A products
0.1 mg / US$ 465 no delivery possible
Quick Overview
Goat anti CDKN2A
Synonyms
anti-CDKN2A antibody, anti-cyclin-dependent kinase inhibitor 2A antibody, anti-HGNC:1787 antibody, anti-ARF antibody, anti-CDK4I antibody, anti-CDKN2 antibody, anti-CMM2 antibody, anti-INK4 antibody, anti-INK4a antibody, anti-MLM antibody, anti-MTS1 antibody, anti-TP16 antibody, anti-p14 antibody, anti-p14ARF antibody, anti-p16 antibody, anti-p16INK4 antibody, anti-p16INK4a antibody, anti-p19 antibody, anti-CDK4 inhibitor p16-INK4 antibody, anti-cell cycle negative regulator beta antibody, anti-cyclin- antibody, melanoma antibody, anti-p16 antibody, anti-inhibits CDK4
Product Description
Goat anti CDKN2A , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Goat |
| Isotype | IgG |
| Catalog Number | NB100-40911 |
| Quantity | 0.1 mg |
| Price | US$ 465 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Goat Polyclonal anti-CDKN2A | |
| Alternate names | anti-CDKN2A antibody, anti-cyclin-dependent kinase inhibitor 2A (melanoma antibody, anti-p16 antibody, anti-inhibits CDK4) antibody, anti-HGNC:1787 antibody, anti-ARF antibody, anti-CDK4I antibody, anti-CDKN2 antibody, anti-CMM2 antibody, anti-INK4 antibody, anti-INK4a antibody, anti-MLM antibody, anti-MTS1 antibody, anti-TP16 antibody, anti-p14 antibody, anti-p14ARF antibody, anti-p16 antibody, anti-p16INK4 antibody, anti-p16INK4a antibody, anti-p19 antibody, anti-CDK4 inhibitor p16-INK4 antibody, anti-cell cycle negative regulator beta antibody, anti-cyclin- antibody |
| Concentration | 0.5 mg/ml |
| Background | This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. |
| Immunogen | Synthetic peptide: C-HARIDAAEGPSDIPD, representing the C Terminus of the human protein according to NP_000068.1 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| Applications | WB |
| Specificity | Species: Human. Other Species have not been tested. Expected cross-reactivity based upon sequence homology: Human |
| References | Mawrin C, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk CK, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk. Alterations of cell cycle regulators in gliomatosis cerebri.. J Neurooncol. 2005 Apr;72(2):115-22. . PMID: 15925990 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 295 | |||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 295 | |||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 305 | |||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 315 | |||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / US$ 445 | |||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / US$ 445 | |||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / US$ 445 | |||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / US$ 465 | |||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / US$ 445 | |||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-40911 CDKN2A'.
