NB100-220 ATM antibody
see related secondary antibodiessee all 81 ATM products
0.1 mg / US$ 515 no delivery possible
Quick Overview
Mouse anti ATM 5C2
Synonyms
Serine-protein kinase ATM, Ataxia telangiectasia mutated, A-T mutated, ,
Product review
Please read our product review about ATM: Antibody Panel to ATM Kinase.
Product Description
Mouse anti ATM 5C2, Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Monkey ( Mky ), Rat ( Rt ), Mouse ( Ms ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 5C2 |
| Catalog Number | NB100-220 |
| Swiss Prot. No. | Q13315 |
| Quantity | 0.1 mg |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Mouse Monoclonal anti-ATM (5C2) | |
| Alternate names | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia telangiectasia gene mutated antibody |
| Concentration | 1 mg/ml |
| Background | ATM-5C2 recognizes full-length ATM, a 370 kDa nuclear phosphoprotein, which is involved in the autosomal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigation. |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 980-1512. Swiss Num.: Q13315 |
| Format | Purification: protein G purified Purity: protein G purified BufferSystem: PBS [pH 7.2] |
| Applications | immunofluorescence 2-10 ug/ml, Western Blot 1-2 ug/ml , Immunoblotting |
| Specificity | Species: Human, Monkey, Rat, Mouse. Other species have not been tested. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Andegeko, Y, et al. (2001) Nuclear Retention of ATM at Sites of DNA Double strand breaks. J Biol Chem 276: 38224-38230.
2. Suzuki, K., Kodama, S. and Watanabe, M. (1999) Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J Biol Chem 274: 25571-25575. 3. Chen, G. and Lee, E.Y-H.P. (1996) The product of the ATM gene is a 370-kDa nuclear phosphoprotein. J Biol Chem 271: 33693-33697. 4. Uziel, T. et al. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22:5612-5621, 2003. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-220 ATM'.
