NB100-1746 p53 antibody
see related secondary antibodiessee all 282 p53 products
0.1 ml / US$ 565 no delivery possible
Quick Overview
Rabbit anti p53
Synonyms
Phosphoprotein p53, TP53, NY-CO-13, TRP53, , Cellular tumor antigen p53, Tumor suppressor p53
Product review
Please read our product review about p53: Antibodies to p53 and p53 interacting proteins.
Product Description
Rabbit anti p53 , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB100-1746 |
| Swiss Prot. No. | P04637 |
| Quantity | 0.1 ml |
| Price | US$ 565 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Rabbit Polyclonal anti-p53 | |
| Alternate names | anti-Cys 51 Stop antibody, anti-HGNC11998 antibody, anti-p53 Cellular Tumor Antigen antibody, anti-p53 Tumor Suppressor antibody, anti-Phosphoproteinp53 antibody, anti-TP53 antibody, anti-Transformation related protein 53 antibody, anti-TRP53 antibody, anti-Tumour Protein p53 antibody |
| Background | Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. |
| Immunogen | The epitope recognized by this antibody maps to a region between residue 50 and 100 of human tumor protein p53 using the numbering given in entry NP 000537.2 (GeneID 7157). Swiss Num.: P04637 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Tris-buffered Saline containing 0.1% BSA |
| Applications | immunohistochemistry 1:100-1:500, |
| Specificity | Species: Human. |
| Storage | Store at 4C. Do not freeze. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB100-1746 p53'.
