GTX74282 Presenilin 2 / PS2 / PSEN2 (Sample) antibody
see related secondary antibodiessee all 25 Presenilin 2 / PS2 / PSEN2 products
20 µl / no delivery possible
Quick Overview
Goat anti Presenilin 2 / PS2 / PSEN2 (Sample)
Synonyms
Presenilin-2, PS-2, AD4, AD5, STM-2, STM2, AD3LP, PSNL2, , Alzheimer disease 4
Product review
Please read our product review about Presenilin 2 / PS2 / PSEN2 (Sample): Antibody Panel to Presenilin 1 + 2.
Product Description
Goat anti Presenilin 2 / PS2 / PSEN2 (Sample) . Product is tested for Frozen sections ( C ), Paraffin Sections ( P )
Properties
| Applications | Frozen sections ( C ), Paraffin Sections ( P ) |
| Reactivity | Goat ( Gt ), Human ( Hu ) |
| Host | Goat |
| Catalog Number | GTX74282 |
| Swiss Prot. No. | P49810 |
| Quantity | 20 µl |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Presenilin-2 Sample antibody | |
| Concentration | antiserum |
| Background | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified. |
| Immunogen | Synthetic peptide corresponding to amino acids 31-47 of Presenilin-2 Swiss Num.: P49810 |
| Format | State: Liquid Purification: Unpurified Purity: Unpurified BufferSystem: Antiserum containing 0.09% sodium azide |
| Applications | IHC-Fr, IHC-P |
| Specificity | Human and goat - Not yet tested in other species |
| Storage | Keep as concentrated solution. Store at 4 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1317B | Goat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1317F | Goat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 295 | |||||
| R1317T | Goat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 295 | |||||
| R1317TR | Goat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1317HRP | Goat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 305 | |||||
| R1317AP | Goat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 315 | |||||
| R1435C2 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy2 | 1 mg / US$ 445 | |||||
| R1435C3 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3 | 1 mg / US$ 445 | |||||
| R1435C35 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy3.5 | 1 mg / US$ 445 | |||||
| R1435C5 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5 | 1 mg / US$ 465 | |||||
| R1435C55 | Goat IgG (H&L) multi-species ads. | ||||||
| Donkey | Cy5.5 | 1 mg / US$ 445 | |||||
| R1416R | Goat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX74282 Presenilin 2 / PS2 / PSEN2 (Sample)'.
